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- Published: July 2025
- Pages: 480
- Tables: 133
- Figures: 70
The global synthetic biology market represents one of the most transformative and rapidly expanding sectors in modern biotechnology, fundamentally reshaping how we approach medicine, agriculture, manufacturing, and environmental challenges. Valued at approximately $16-18 billion in 2024, the market is projected to experience explosive growth, driven by advances in genetic engineering, computational design, and automated biological systems.
The synthetic biology market is experiencing robust growth at a compound annual growth rate (CAGR) of 20.6-28.63%, fueled by several converging factors. The dramatic reduction in DNA sequencing and synthesis costs has democratized access to genetic engineering tools, while artificial intelligence and machine learning algorithms have accelerated the design of biological systems. Rising demand for bio-based products, growing demand for personalized therapies, and advancements in DNA sequencing and synthesis technologies are key factors accelerating market growth.
The pharmaceutical and healthcare sector dominates the market landscape. This dominance stems from synthetic biology's impact on drug discovery, personalized medicine, and therapeutic development. The technology enables the creation of novel biologics, synthetic vaccines, and engineered cell therapies that address previously untreatable conditions.
Despite remarkable growth prospects, the synthetic biology market faces several challenges. Regulatory uncertainty remains a significant barrier, as existing frameworks struggle to keep pace with rapid technological advancement. Public acceptance and ethical concerns surrounding genetic engineering applications require ongoing attention and transparent communication about benefits and risks. Technical challenges include scaling laboratory innovations to industrial production, ensuring reliability and predictability of engineered biological systems, and developing standardized tools and methodologies. The complexity of biological systems continues to present engineering challenges that require sustained research and development investment.
The synthetic biology market represents a paradigm shift toward programmable biology, where engineered biological systems address global challenges in healthcare, food security, climate change, and sustainable manufacturing. As the technology matures and costs continue to decline, synthetic biology is poised to become a cornerstone of the 21st-century bioeconomy, creating unprecedented opportunities for innovation and economic growth while addressing humanity's most pressing challenges.
The Global Synthetic Biology (Synbio) Market 2026-2036 represents the most comprehensive analysis of one of biotechnology's fastest-growing sectors, providing essential intelligence for investors, industry leaders, and strategic planners. This definitive market report delivers critical insights into the transformative synthetic biology landscape, covering market dynamics, technological innovations, competitive positioning, and growth opportunities across key application areas including pharmaceuticals, agriculture, industrial biotechnology, and environmental solutions.
Report contents include:
- Technology-based revenue projections
- Product type market dynamics (oligonucleotides, enzymes, synthetic genes, synthetic cells)
- Regional market opportunities across North America, Europe, Asia-Pacific, and emerging markets
- Application-specific growth drivers spanning 13 major industry verticals
- Advanced biomanufacturing analysis encompasses:
- Batch versus continuous bioprocessing optimization
- Cell-free synthesis systems and scalability challenges
- Fermentation process innovations and efficiency improvements
- Biofilm-based production and microfluidic manufacturing systems
- Photobioreactor technologies and membrane bioreactor applications
- Markets & Applications:
- Biofuels & Energy: Bioethanol, biodiesel, biogas, renewable diesel, biojet fuel, and hydrogen production
- Bio-based Chemicals: Industrial chemicals, specialty chemicals, and sustainable chemical manufacturing
- Bioplastics & Biopolymers: PLA, PHA, bio-PET, and next-generation biodegradable materials
- Healthcare & Pharmaceuticals: Drug discovery, gene therapy, vaccine production, personalized medicine
- Agriculture & Food: Crop enhancement, biofertilizers, biopesticides, alternative proteins
- Textiles & Materials: Bio-based fibers, sustainable leather alternatives, mycelium materials
- Environmental Solutions: Bioremediation, carbon capture, pollution control technologies
- Regional Market Analysis & Growth Opportunities
- Competitive Landscape & Company Profiles. The report features comprehensive profiles of 320+ leading synthetic biology companies, providing detailed analysis of business models, product portfolios, financial performance, and strategic positioning. Our competitive intelligence covers established biotechnology leaders, emerging startups, and technology platform providers across the synthetic biology value chain. Companies profiled include Aanika Biosciences, Aemetis Inc., AEP Polymers, Afyren, AgBiome, AgriSea NZ Seaweed Ltd, Agrivida, Ainnocence, ÄIO, AI Proteins, Algal Bio Co. Ltd., Algenol, AlgiKnit, Algiecel ApS, Alpha Biofuels Singapore Pte Ltd, Allonnia LLC, Allozymes, Alt.Leather, Alto Neuroscience, Amano Enzyme Inc., AmphiStar, Amply Discovery, AMSilk GmbH, Amyris, Andes Ag Inc., Ansa Biotechnologies, Antheia, Apeel Sciences, Aralez Bio, Arctic Biomaterials Oy, Ardra Bio, Arkeon, Arsenale Bioyards, Arzeda, Asimov, Atantares, Autolus, AVA Biochem AG, Avantium B.V., Azolla, Axcelon Biopolymers Corporation, Basecamp Research, BBCA Biochemical & GALACTIC Lactic Acid Co. Ltd., Benefuel Inc., BioBetter, Bioextrax AB, Bio Fab NZ, Biokemik, BIOLO, Biomason Inc., Biomemory, Bioplastech Ltd, BioSmart Nano, Biotic Circular Technologies Ltd., Biosyntia, Biotecam, Bioweg, bit.bio, Bloom Biorenewables SA, BluCon Biotech GmbH, Blue BioFuels Inc., Bluepha Beijing Lanjing Microbiology Technology Co. Ltd., Bon Vivant, Bolt Threads, Bosk Bioproducts Inc., Bowil Biotech Sp. z o.o., Braskem SA, Brightseed, Bucha Bio Inc., C1 Green Chemicals AG, C16 Biosciences, CABIO Biotech Wuhan Co Ltd, California Cultured, Calysta, Camena Bioscience, Capra Biosciences, Carbios, Cargill, Calyxt, Cascade Biocatalysts, Cass Materials Pty Ltd, Catalyxx, Cathy Biotech Inc., Cauldron Ferm, Cemvita Factory Inc., ChainCraft, Checkerspot, Chitose Bio Evolution Pte Ltd., CinderBio, Circe, CJ Biomaterials Inc., Clean Food Group, Codagenix, Codexis, Colossal Biosciences, Colipi, Colorifix, Conagen, Constructive Bio, Cysbio, Danimer Scientific, Debut Biotechnology, Deep Branch Biotechnology, Demetrix, Dispersa, DMC Biotechnologies, DNA Script, Domsjö Fabriker AB, DoriNano, DuPont, Earli, Ecovative Design LLC, Eco Fuel Technology Inc, Eden Brew, EggPlant Srl, Eligo Bioscience, Elo Life Systems, Emerging Fuels Technology EFT, Enduro Genetics, EnginZyme AB, Eni S.p.A., EnPlusOne Biosciences, Enzymaster, Enzymit, Erebagen, Esphera SynBio, Euglena Co. Ltd., Eversyn, Evozyne, FabricNano, Fermentalg, eniferBio, ENOUGH, Epoch Biodesign, Evolved By Nature, Evonetix Limited, Evonik Industries AG, EV Biotech, Farmless, Fermelanta and more......
- Investment Analysis & Market Forecasts: insights into funding trends, valuation metrics, and growth opportunities across synthetic biology segments. The report examines venture capital flows, public market performance, and strategic acquisition activity, delivering essential intelligence for investment decision-making.
- Market sizing and growth projections through 2036
- Technology readiness levels and commercialization timelines
- Risk assessment and regulatory consideration
- Strategic partnership opportunities and M&A activity
- Technology Roadmap & Future Outlook
- Future market outlook:
- Emerging applications in space biotechnology and climate engineering
- Convergence with artificial intelligence and nanotechnology
- Regulatory evolution and standardization frameworks
- Global market expansion and democratization trends
This essential market intelligence report serves as the definitive guide for understanding synthetic biology's transformative potential, providing actionable insights for strategic planning, investment decisions, and market positioning in one of biotechnology's most dynamic sectors.
1 EXECUTIVE SUMMARY 25
- 1.1 Overview of the global synthetic biology market 25
- 1.2 Difference between synthetic biology and genetic engineering 27
- 1.3 Market size and growth projections 27
- 1.3.1 By Technology 27
- 1.3.2 By Product Type 29
- 1.3.3 By Market 31
- 1.3.4 By Region 33
- 1.4 Major trends and drivers 35
- 1.5 Investments in synthetic biology 36
- 1.6 Technology roadmap 37
- 1.7 Industrial biotechnology value chain 38
2 INTRODUCTION 40
- 2.1 What is synthetic biology? 40
- 2.2 Comparison with conventional processes 40
- 2.3 Applications 41
- 2.4 Advantages 42
- 2.5 Sustainability 42
- 2.6 Synthetic Biology for the Circular Economy 43
3 TECHNOLOGY ANALYSIS 45
- 3.1 Biomanufacturing processes 45
- 3.1.1 Batch biomanufacturing 47
- 3.1.2 Continuous biomanufacturing 48
- 3.1.3 Fermentation Processes 48
- 3.1.4 Cell-free synthesis 49
- 3.1.5 Biofilm-based production 51
- 3.1.6 Microfluidic systems 52
- 3.1.7 Photobioreactors 52
- 3.1.8 Membrane bioreactors 53
- 3.1.9 Plant cell culture 54
- 3.1.10 Mammalian cell culture 54
- 3.1.11 Bioprinting 55
- 3.2 Cell factories for biomanufacturing 58
- 3.3 Technology Overview 59
- 3.3.1 Metabolic engineering 60
- 3.3.2 Gene and DNA synthesis 64
- 3.3.3 Gene Synthesis and Assembly 65
- 3.3.4 Genome engineering 66
- 3.3.4.1 CRISPR 67
- 3.3.4.1.1 CRISPR/Cas9-modified biosynthetic pathways 67
- 3.3.4.1.2 TALENs 68
- 3.3.4.1.3 ZFNs 68
- 3.3.4.1 CRISPR 67
- 3.3.5 Protein/Enzyme Engineering 70
- 3.3.6 Synthetic genomics 71
- 3.3.6.1 Principles of Synthetic Genomics 71
- 3.3.6.2 Synthetic Chromosomes and Genomes 72
- 3.3.7 Strain construction and optimization 74
- 3.3.8 Smart bioprocessing 74
- 3.3.9 Chassis organisms 75
- 3.3.10 Biomimetics 76
- 3.3.11 Sustainable materials 77
- 3.3.12 Robotics and automation 77
- 3.3.12.1 Robotic cloud laboratories 78
- 3.3.12.2 Automating organism design 78
- 3.3.12.3 Artificial intelligence and machine learning 78
- 3.3.13 Bioinformatics and computational tools 79
- 3.3.13.1 Role of Bioinformatics in Synthetic Biology 79
- 3.3.13.2 Computational Tools for Design and Analysis 80
- 3.3.14 Xenobiology and expanded genetic alphabets 82
- 3.3.15 Biosensors and bioelectronics 82
- 3.3.16 Feedstocks 83
- 3.3.16.1 C1 feedstocks 86
- 3.3.16.1.1 Advantages 86
- 3.3.16.1.2 Pathways 87
- 3.3.16.1.3 Challenges 88
- 3.3.16.1.4 Non-methane C1 feedstocks 88
- 3.3.16.1.5 Gas fermentation 89
- 3.3.16.2 C2 feedstocks 89
- 3.3.16.3 Biological conversion of CO2 89
- 3.3.16.4 Food processing wastes 93
- 3.3.16.5 Lignocellulosic biomass 93
- 3.3.16.6 Syngas 94
- 3.3.16.7 Glycerol 94
- 3.3.16.8 Methane 94
- 3.3.16.9 Municipal solid wastes 97
- 3.3.16.10 Plastic wastes 98
- 3.3.16.11 Plant oils 98
- 3.3.16.12 Starch 99
- 3.3.16.13 Sugars 100
- 3.3.16.14 Used cooking oils 100
- 3.3.16.15 Green hydrogen production 101
- 3.3.16.16 Blue hydrogen production 102
- 3.3.16.1 C1 feedstocks 86
- 3.3.17 Marine biotechnology 104
- 3.3.17.1 Cyanobacteria 105
- 3.3.17.2 Macroalgae 106
- 3.3.17.3 Companies 107
4 MARKET ANALYSIS 109
- 4.1 Market trends and drivers 109
- 4.2 Industry challenges and constraints 109
- 4.3 Synthetic biology in the bioeconomy 110
- 4.4 SWOT analysis 111
- 4.5 Synthetic biology markets 113
- 4.5.1 Biofuels 113
- 4.5.1.1 Solid Biofuels 115
- 4.5.1.2 Liquid Biofuels 116
- 4.5.1.3 Gaseous Biofuels 116
- 4.5.1.4 Conventional Biofuels 117
- 4.5.1.5 Advanced Biofuels 117
- 4.5.1.6 Feedstocks 118
- 4.5.1.6.1 First-generation (1-G) 120
- 4.5.1.6.2 Second-generation (2-G) 121
- 4.5.1.6.2.1 Lignocellulosic wastes and residues 122
- 4.5.1.6.2.2 Biorefinery lignin 123
- 4.5.1.6.3 Third-generation (3-G) 126
- 4.5.1.6.3.1 Algal biofuels 126
- 4.5.1.6.3.1.1 Properties 127
- 4.5.1.6.3.1.2 Advantages 127
- 4.5.1.6.3.1 Algal biofuels 126
- 4.5.1.6.4 Fourth-generation (4-G) 128
- 4.5.1.6.5 Energy crops 128
- 4.5.1.6.6 Agricultural residues 129
- 4.5.1.6.7 Manure, sewage sludge and organic waste 129
- 4.5.1.6.8 Forestry and wood waste 129
- 4.5.1.6.9 Feedstock costs 130
- 4.5.1.7 Synthetic biology approaches for biofuel production 130
- 4.5.1.8 Bioethanol 131
- 4.5.1.8.1 Ethanol to jet fuel technology 132
- 4.5.1.8.2 Methanol from pulp & paper production 133
- 4.5.1.8.3 Sulfite spent liquor fermentation 133
- 4.5.1.8.4 Gasification 133
- 4.5.1.8.4.1 Biomass gasification and syngas fermentation 133
- 4.5.1.8.4.2 Biomass gasification and syngas thermochemical conversion 134
- 4.5.1.8.5 CO2 capture and alcohol synthesis 134
- 4.5.1.8.6 Biomass hydrolysis and fermentation 134
- 4.5.1.8.7 Separate hydrolysis and fermentation 135
- 4.5.1.8.7.1 Simultaneous saccharification and fermentation (SSF) 135
- 4.5.1.8.7.2 Pre-hydrolysis and simultaneous saccharification and fermentation (PSSF) 135
- 4.5.1.8.7.3 Simultaneous saccharification and co-fermentation (SSCF) 136
- 4.5.1.8.7.4 Direct conversion (consolidated bioprocessing) (CBP) 136
- 4.5.1.9 Biodiesel 136
- 4.5.1.10 Biogas 139
- 4.5.1.10.1 Biomethane 140
- 4.5.1.10.2 Feedstocks 141
- 4.5.1.10.3 Anaerobic digestion 142
- 4.5.1.11 Renewable diesel 143
- 4.5.1.12 Biojet fuel 144
- 4.5.1.13 Algal biofuels (blue biotech) 148
- 4.5.1.13.1 Conversion pathways 148
- 4.5.1.13.2 Market challenges 149
- 4.5.1.13.3 Prices 150
- 4.5.1.13.4 Producers 150
- 4.5.1.14 Biohydrogen 151
- 4.5.1.14.1 Biological Conversion Routes 153
- 4.5.1.14.1.1 Bio-photochemical Reaction 153
- 4.5.1.14.1.2 Fermentation and Anaerobic Digestion 153
- 4.5.1.14.1 Biological Conversion Routes 153
- 4.5.1.15 Biobutanol 154
- 4.5.1.16 Bio-based methanol 155
- 4.5.1.16.1 Anaerobic digestion 157
- 4.5.1.16.2 Biomass gasification 158
- 4.5.1.16.3 Power to Methane 159
- 4.5.1.17 Bioisoprene 159
- 4.5.1.18 Fatty Acid Esters 159
- 4.5.2 Bio-based chemicals 160
- 4.5.2.1 Acetic acid 161
- 4.5.2.2 Adipic acid 161
- 4.5.2.3 Aldehydes 162
- 4.5.2.4 Acrylic acid 163
- 4.5.2.5 Bacterial cellulose 163
- 4.5.2.6 1,4-Butanediol (BDO) 166
- 4.5.2.7 Bio-DME 167
- 4.5.2.8 Dodecanedioic acid (DDDA) 167
- 4.5.2.9 Ethylene 168
- 4.5.2.10 3-Hydroxypropionic acid (3-HP) 168
- 4.5.2.11 1,3-Propanediol (1,3-PDO) 169
- 4.5.2.12 Itaconic acid 170
- 4.5.2.13 Lactic acid (D-LA) 171
- 4.5.2.14 1,5-diaminopentane (DA5) 171
- 4.5.2.15 Tetrahydrofuran (THF) 172
- 4.5.2.16 Malonic acid 173
- 4.5.2.17 Monoethylene glycol (MEG) 174
- 4.5.2.18 Propylene 174
- 4.5.2.19 Succinic acid (SA) 175
- 4.5.2.20 Triglycerides 176
- 4.5.2.21 Enzymes 177
- 4.5.2.22 Vitamins 177
- 4.5.2.23 Antibiotics 177
- 4.5.3 Bioplastics and Biopolymers 178
- 4.5.3.1 Polylactic acid (PLA) 179
- 4.5.3.2 PHAs 180
- 4.5.3.2.1 Types 182
- 4.5.3.2.1.1 PHB 183
- 4.5.3.2.1.2 PHBV 184
- 4.5.3.2.2 Synthesis and production processes 185
- 4.5.3.2.3 Commercially available PHAs 187
- 4.5.3.2.1 Types 182
- 4.5.3.3 Bio-PET 188
- 4.5.3.4 Starch blends 189
- 4.5.3.5 Protein-based bioplastics 189
- 4.5.4 Bioremediation 191
- 4.5.5 Biocatalysis 192
- 4.5.5.1 Biotransformations 192
- 4.5.5.2 Cascade biocatalysis 192
- 4.5.5.3 Co-factor recycling 193
- 4.5.5.4 Immobilization 193
- 4.5.6 Food and Nutraceutical Ingredients 193
- 4.5.6.1 Alternative Proteins 194
- 4.5.6.2 Natural Sweeteners 195
- 4.5.6.3 Natural Flavors and Fragrances 195
- 4.5.6.4 Texturants and Thickeners 196
- 4.5.6.5 Nutraceuticals and Supplements 196
- 4.5.7 Sustainable agriculture 196
- 4.5.7.1 Crop Improvement and Trait Development 196
- 4.5.7.2 Plant-Microbe Interactions and Symbiosis 197
- 4.5.7.3 Biofertilizers 197
- 4.5.7.3.1 Overview 197
- 4.5.7.3.2 Companies 198
- 4.5.7.4 Biopesticides 198
- 4.5.7.4.1 Overview 198
- 4.5.7.4.2 Companies 198
- 4.5.7.5 Biostimulants 199
- 4.5.7.5.1 Overview 199
- 4.5.7.5.2 Companies 199
- 4.5.7.6 Crop Biotechnology 200
- 4.5.7.6.1 Genetic engineering 200
- 4.5.7.6.2 Genome editing 200
- 4.5.7.6.3 Companies 201
- 4.5.8 Textiles 201
- 4.5.8.1 Bio-Based Fibers 202
- 4.5.8.1.1 Lyocell 202
- 4.5.8.1.2 Bacterial cellulose 202
- 4.5.8.1.3 Algae textiles 203
- 4.5.8.2 Bio-based leather 203
- 4.5.8.2.1 Properties of bio-based leathers 206
- 4.5.8.2.1.1 Tear strength 207
- 4.5.8.2.1.2 Tensile strength 207
- 4.5.8.2.1.3 Bally flexing 207
- 4.5.8.2.2 Comparison with conventional leathers 208
- 4.5.8.2.3 Comparative analysis of bio-based leathers 211
- 4.5.8.2.1 Properties of bio-based leathers 206
- 4.5.8.3 Plant-based leather 211
- 4.5.8.3.1 Overview 211
- 4.5.8.3.2 Production processes 212
- 4.5.8.3.2.1 Feedstocks 212
- 4.5.8.3.2.2 Agriculture Residues 212
- 4.5.8.3.2.3 Food Processing Waste 212
- 4.5.8.3.2.4 Invasive Plants 213
- 4.5.8.3.2.5 Culture-Grown Inputs 213
- 4.5.8.3.2.6 Textile-Based 213
- 4.5.8.3.2.7 Bio-Composite 214
- 4.5.8.3.3 Products 214
- 4.5.8.3.4 Market players 215
- 4.5.8.4 Mycelium leather 216
- 4.5.8.4.1 Overview 216
- 4.5.8.4.2 Production process 217
- 4.5.8.4.2.1 Growth conditions 218
- 4.5.8.4.2.2 Tanning Mycelium Leather 218
- 4.5.8.4.2.3 Dyeing Mycelium Leather 219
- 4.5.8.4.3 Products 219
- 4.5.8.4.4 Market players 220
- 4.5.8.5 Microbial leather 220
- 4.5.8.5.1 Overview 220
- 4.5.8.5.2 Production process 221
- 4.5.8.5.3 Fermentation conditions 221
- 4.5.8.5.4 Harvesting 222
- 4.5.8.5.5 Products 222
- 4.5.8.5.6 Market players 225
- 4.5.8.6 Lab grown leather 226
- 4.5.8.6.1 Overview 226
- 4.5.8.6.2 Production process 226
- 4.5.8.6.3 Products 227
- 4.5.8.6.4 Market players 227
- 4.5.8.7 Protein-based leather 228
- 4.5.8.7.1 Overview 228
- 4.5.8.7.2 Production process 228
- 4.5.8.7.3 Commercial activity 229
- 4.5.8.8 Recombinant Materials 229
- 4.5.8.9 Sustainable Processing 230
- 4.5.8.1 Bio-Based Fibers 202
- 4.5.9 Packaging 230
- 4.5.9.1 Polyhydroxyalkanoates (PHA) 230
- 4.5.9.2 Applications 231
- 4.5.9.2.1 Vials, bottles, and containers 232
- 4.5.9.2.2 Disposable items and household goods 233
- 4.5.9.2.3 Food packaging 233
- 4.5.9.2.4 Wet wipes and diapers 234
- 4.5.9.3 Proteins 234
- 4.5.9.4 Algae-based 236
- 4.5.9.5 Mycelium 237
- 4.5.9.6 Antimicrobial films and agents 237
- 4.5.10 Healthcare and Pharmaceuticals 238
- 4.5.10.1 Drug discovery and development 240
- 4.5.10.2 Gene therapy and regenerative medicine 241
- 4.5.10.3 Vaccine production 242
- 4.5.10.4 Personalized medicine 244
- 4.5.10.5 Diagnostic tools and biosensors 246
- 4.5.10.6 Companies 247
- 4.5.11 Cosmetics 247
- 4.5.12 Surfactants and detergents 248
- 4.5.13 Construction materials 249
- 4.5.13.1 Bioconcrete 249
- 4.5.13.2 Microalgae biocement 251
- 4.5.13.3 Mycelium materials 253
- 4.5.1 Biofuels 113
- 4.6 Global market revenues 2018-2036 254
- 4.6.1 By Technology 254
- 4.6.2 By Product Type 256
- 4.6.3 By Market 258
- 4.6.4 By Region 260
- 4.7 Future Market Outlook 262
5 COMPANY PROFILES 264 (321 company profiles)
6 APPENDIX 464
- 6.1 Research Methodology 464
- 6.2 Glossary of Terms 464
7 REFERENCES 466
List of Tables
- Table 1. Comparison of synthetic biology and genetic engineering. 27
- Table 2. Global Revenues for Synthetic Biology by Technology, 2018-2036 (Billion USD). 28
- Table 3. Global Revenues for Synthetic Biology by Product Type, 2018-2036 (Billion USD). 30
- Table 4. Global revenues for synthetic biology, by market, 2018-2036 (Billion USD). 32
- Table 5. Global revenues for synthetic biology, by region, 2018-2036 (Billion USD). 34
- Table 6. Major trends and drivers in synthetic biology. 35
- Table 7. Investments in synthetic biology. 36
- Table 8. Phase 1: Foundation & Optimization (2025-2027). 37
- Table 9. Phase 2: Integration & Scale (2028-2030). 37
- Table 10. Phase 3: Transformation & Convergence (2031-2033). 37
- Table 11. Phase 4: Maturation & Optimization (2034-2036). 38
- Table 12. Differences between synthetic biology and conventional processes. 40
- Table 13. Main application areas for synthetic biology. 41
- Table 14. Advantages of synthetic biology. 42
- Table 15. Key biomanufacturing processes utilized in synthetic biology. 45
- Table 16. Molecules produced through industrial biomanufacturing. 46
- Table 17. Continuous vs batch biomanufacturing 47
- Table 18. Key fermentation parameters in batch vs continuous biomanufacturing processes. 47
- Table 19. Synthetic biology fermentation processes. 49
- Table 20. Cell-free versus cell-based systems 49
- Table 21. Comparison of the biomanufacturing processes in synthetic biology. 56
- Table 22. Major microbial cell factories used in industrial biomanufacturing. 58
- Table 23. Core stages - Design, Build and Test. 60
- Table 24. Key tools and techniques used in metabolic engineering for pathway optimization. 61
- Table 25. Key applications of metabolic engineering. 62
- Table 26. Main DNA synthesis technologies 64
- Table 27. Main gene assembly methods. 65
- Table 28. Key applications of genome engineering. 69
- Table 29. Engineered proteins in industrial applications. 71
- Table 30.Key computational tools and their applications in synthetic biology. 80
- Table 31. Feedstocks for synthetic biology. 83
- Table 32. Products from C1 feedstocks in white biotechnology. 88
- Table 33. C2 Feedstock Products. 89
- Table 34. CO2 derived products via biological conversion-applications, advantages and disadvantages. 91
- Table 35. Production capacities of biorefinery lignin producers. 93
- Table 36. Common starch sources that can be used as feedstocks for producing biochemicals. 99
- Table 37. Biomass processes summary, process description and TRL. 102
- Table 38. Pathways for hydrogen production from biomass. 103
- Table 39. Overview of alginate-description, properties, application and market size. 104
- Table 40. Blue biotechnology companies. 107
- Table 41. Market trends and drivers in synthetic biology. 109
- Table 42. Industry challenges and restraints in synthetic biology. 109
- Table 43. Key markets and applications for synthetic biology. 113
- Table 44. Comparison of biofuels. 114
- Table 45. Categories and examples of solid biofuel. 115
- Table 46. Comparison of biofuels and e-fuels to fossil and electricity. 118
- Table 47. Classification of biomass feedstock. 118
- Table 48. Biorefinery feedstocks. 119
- Table 49. Feedstock conversion pathways. 119
- Table 50. First-Generation Feedstocks. 120
- Table 51. Lignocellulosic ethanol plants and capacities. 122
- Table 52. Comparison of pulping and biorefinery lignins. 123
- Table 53. Commercial and pre-commercial biorefinery lignin production facilities and processes 124
- Table 54. Operating and planned lignocellulosic biorefineries and industrial flue gas-to-ethanol. 125
- Table 55. Properties of microalgae and macroalgae. 127
- Table 56. Yield of algae and other biodiesel crops. 128
- Table 57. Processes in bioethanol production. 135
- Table 58. Microorganisms used in CBP for ethanol production from biomass lignocellulosic. 136
- Table 59. Biodiesel by generation. 137
- Table 60. Biodiesel production techniques. 138
- Table 61. Biofuel production cost from the biomass pyrolysis process. 139
- Table 62. Biogas feedstocks. 141
- Table 63. Advantages and disadvantages of Bio-aviation fuel. 145
- Table 64. Production pathways for Bio-aviation fuel. 145
- Table 65. Current and announced Bio-aviation fuel facilities and capacities. 147
- Table 66. Algae-derived biofuel producers. 150
- Table 67. Markets and applications for biohydrogen. 152
- Table 68. Comparison of different Bio-H2 production pathways. 152
- Table 69. Properties of petrol and biobutanol. 154
- Table 70. Comparison of biogas, biomethane and natural gas. 157
- Table 71. Biobased chemicals that can be produced using synthetic biology approaches. 160
- Table 72. Applications of bio-based caprolactam. 162
- Table 73. Applications of bio-based acrylic acid. 163
- Table 74. Applications of bio-based 1,4-Butanediol (BDO). 166
- Table 75. Applications of bio-based ethylene. 168
- Table 76. Biobased feedstock sources for 3-HP. 169
- Table 77. Applications of 3-HP. 169
- Table 78. Applications of bio-based 1,3-Propanediol (1,3-PDO). 170
- Table 79. Biobased feedstock sources for itaconic acid. 170
- Table 80. Applications of bio-based itaconic acid. 170
- Table 81. Biobased feedstocks that can be used to produce 1,5-diaminopentane (DA5). 172
- Table 82. Applications of DN5. 172
- Table 83. Applications of bio-based Tetrahydrofuran (THF). 173
- Table 84. Markets and applications for malonic acid. 173
- Table 85. Biobased feedstock sources for MEG. 174
- Table 86. Applications of bio-based MEG. 174
- Table 87. Applications of bio-based propylene. 175
- Table 88. Biobased feedstock sources for Succinic acid. 176
- Table 89. Applications of succinic acid. 176
- Table 90. Bioplastics and bioplastic precursors synthesized via white biotechnology processes . 178
- Table 91. Polylactic acid (PLA) market analysis-manufacture, advantages, disadvantages and applications. 179
- Table 92. PLA producers and production capacities. 180
- Table 93.Types of PHAs and properties. 183
- Table 94. Comparison of the physical properties of different PHAs with conventional petroleum-based polymers. 184
- Table 95. Polyhydroxyalkanoate (PHA) extraction methods. 186
- Table 96. Commercially available PHAs. 188
- Table 97. Types of protein based-bioplastics, applications and companies. 190
- Table 98. Applications of white biotechnology in bioremediation and environmental remediation. 191
- Table 99. Companies developing fermentation-derived food. 194
- Table 100. Biofertilizer companies. 198
- Table 101. Biopesticides companies. 198
- Table 102. Biostimulants companies. 199
- Table 103. Crop biotechnology companies. 201
- Table 104. Types of sustainable alternative leathers. 205
- Table 105. Properties of bio-based leathers. 206
- Table 106. Comparison with conventional leathers. 208
- Table 107. Price of commercially available sustainable alternative leather products. 209
- Table 108. Comparative analysis of sustainable alternative leathers. 211
- Table 109. Key processing steps involved in transforming plant fibers into leather materials. 212
- Table 110. Current and emerging plant-based leather products. 214
- Table 111. Companies developing plant-based leather products. 215
- Table 112. Overview of mycelium-description, properties, drawbacks and applications. 216
- Table 113. Companies developing mycelium-based leather products. 220
- Table 114. Types of microbial-derived leather alternative. 223
- Table 115. Companies developing microbial leather products. 225
- Table 116. Companies developing plant-based leather products. 227
- Table 117. Types of protein-based leather alternatives. 228
- Table 118. Companies developing protein based leather. 229
- Table 119. Applications, advantages and disadvantages of PHAs in packaging. 231
- Table 120. Types of protein based-bioplastics, applications and companies. 234
- Table 121. Overview of alginate-description, properties, application and market size. 236
- Table 122. Pharmaceutical applications of synthetic biology. 239
- Table 123. companies involved in synthetic biology for gene therapy and regenerative medicine 242
- Table 124. Companies involved in synthetic biology for vaccine production. 243
- Table 125. Companies involved in synthetic biology for personalized medicine. 245
- Table 126. Synthetic biology companies in healthcare and pharmaceuticals. 247
- Table 127. Applications of biotechnology in the cosmetics industry. 248
- Table 128. Sustainable biomanufacturing of surfactants and detergents. 249
- Table 129. Global Revenues for Synthetic Biology by Technology, 2018-2036 (Billion USD). 255
- Table 130. Global Revenues for Synthetic Biology by Product Type, 2018-2036 (Billion USD). 257
- Table 131. Global revenues for synthetic biology, by market, 2018-2036 (Billion USD). 259
- Table 132. Global revenues for synthetic biology, by region, 2018-2036 (Billion USD). 261
- Table 133. Glossary of Terms. 464
List of Figures
- Figure 1. Global Revenues for Synthetic Biology by Technology, 2018-2036 (Billion USD). 29
- Figure 2. Global Revenues for Synthetic Biology by Product Type, 2018-2036 (Billion USD). 31
- Figure 3. Global revenues for synthetic biology, by market, 2018-2036 (Billion USD). 33
- Figure 4. Global revenues for synthetic biology, by region, 2018-2036 (Billion USD). 34
- Figure 6. Industrial biotechnology value chain. 39
- Figure 7. Cell-free and cell-based protein synthesis systems. 51
- Figure 8. CRISPR/Cas9 & Targeted Genome Editing. 68
- Figure 9. Genetic Circuit-Assisted Smart Microbial Engineering. 75
- Figure 10. Microbial Chassis Development for Natural Product Biosynthesis. 76
- Figure 11. LanzaTech gas-fermentation process. 90
- Figure 12. Schematic of biological CO2 conversion into e-fuels. 91
- Figure 13. Overview of biogas utilization. 95
- Figure 14. Biogas and biomethane pathways. 96
- Figure 15. Schematic overview of anaerobic digestion process for biomethane production. 97
- Figure 16. BLOOM masterbatch from Algix. 105
- Figure 17. SWOT analysis: synthetic biology. 112
- Figure 18. Schematic of a biorefinery for production of carriers and chemicals. 124
- Figure 19. Range of biomass cost by feedstock type. 130
- Figure 20. Overview of biogas utilization. 140
- Figure 21. Biogas and biomethane pathways. 141
- Figure 22. Schematic overview of anaerobic digestion process for biomethane production. 143
- Figure 23. Algal biomass conversion process for biofuel production. 149
- Figure 24. Pathways for algal biomass conversion to biofuels. 151
- Figure 25. Biobutanol production route. 155
- Figure 26. Renewable Methanol Production Processes from Different Feedstocks. 156
- Figure 27. Production of biomethane through anaerobic digestion and upgrading. 158
- Figure 28. Production of biomethane through biomass gasification and methanation. 158
- Figure 29. Production of biomethane through the Power to methane process. 159
- Figure 30. Overview of Toray process. 161
- Figure 31. Bacterial nanocellulose shapes 165
- Figure 32. PHA family. 183
- Figure 33. AlgiKicks sneaker, made with the Algiknit biopolymer gel. 203
- Figure 34. Conceptual landscape of next-gen leather materials. 204
- Figure 35. Hermès bag made of MycoWorks' mycelium leather. 220
- Figure 36. Ganni blazer made from bacterial cellulose. 224
- Figure 37. Bou Bag by GANNI and Modern Synthesis. 225
- Figure 38. Paper cups lined with home-compostable PHA. 231
- Figure 39. Amorphous PHA Cosmetics Jar. 233
- Figure 40. Types of bio-based materials used for antimicrobial food packaging application. 238
- Figure 41. Self-healing bacteria crack filler for concrete. 250
- Figure 42. BioMason cement. 251
- Figure 43. Microalgae based biocement masonry bloc. 252
- Figure 44. Typical structure of mycelium-based foam. 253
- Figure 45. Commercial mycelium composite construction materials. 254
- Figure 46. Global Revenues for Synthetic Biology by Technology, 2018-2036 (Billion USD). 256
- Figure 47. Global Revenues for Synthetic Biology by Product Type, 2018-2036 (Billion USD). 258
- Figure 48. Global revenues for synthetic biology, by market, 2018-2036 (Billion USD). 260
- Figure 49. Global revenues for synthetic biology, by region, 2018-2036 (Billion USD). 262
- Figure 50. Jelly-like seaweed-based nanocellulose hydrogel. 267
- Figure 51. Algiknit yarn. 272
- Figure 52. ALGIECEL PhotoBioReactor. 273
- Figure 53. BIOLO e-commerce mailer bag made from PHA. 295
- Figure 54. Domsjö process. 331
- Figure 55. Mushroom leather. 334
- Figure 56. PHA production process. 352
- Figure 57. Light Bio Bioluminescent plants. 376
- Figure 58. Lignin gel. 377
- Figure 59. BioFlex process. 380
- Figure 60. TransLeather. 384
- Figure 61. Reishi. 395
- Figure 62. Compostable water pod. 403
- Figure 63. Precision Photosynthesis™ technology. 421
- Figure 64. Enfinity cellulosic ethanol technology process. 423
- Figure 65. Fabric consisting of 70 per cent wool and 30 per cent Qmilk. 424
- Figure 66. Lyocell process. 435
- Figure 67. Spider silk production. 440
- Figure 68. Corbion FDCA production process. 450
- Figure 69. UPM biorefinery process. 454
- Figure 70. The Proesa® Process. 457
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