
cover
- Published: August 2026
- Pages: 689
- Tables: 306
- Figures: 26
Industrial biomanufacturing uses living systems — microbes, mammalian, plant and insect cells, and increasingly cell-free enzymatic platforms — to produce molecules that would otherwise be made from petrochemical feedstocks or extracted from natural sources. It spans six commercial domains: biopharmaceuticals, industrial enzymes, biofuels, bioplastics, biochemicals and bio-agritech. The sector's economic case rests on three arguments rather than one. The first is decarbonisation: biological routes displace fossil feedstocks across chemicals, fuels, materials and food ingredients, and where carbon pricing tightens the cost gap narrows structurally rather than cyclically. The second is supply-chain resilience, since fermentation can be sited close to demand and run on local or waste-derived carbon. This has become explicit policy: the United States enacted the BIOSECURE Act in December 2025 and its National Security Commission on Emerging Biotechnology has identified limited domestic scale-up capacity as a structural weakness, while China has published target product lists to direct investment. The third is value capture — biomanufacturing creates new industrial ecosystems in strain design, bioprocess engineering and downstream separation rather than merely substituting inputs.
Biopharmaceuticals remain the largest value pool, with an addressable market approaching $1 trillion by 2030 across monoclonal antibodies, vaccines, recombinant proteins and the faster-growing cell, gene and RNA therapeutic segments. Industrial enzymes represent a mature multi-billion dollar market. Biofuels are the largest volume segment, and bioplastics, biochemicals and bio-agritech expanding from smaller bases. The technology frontier is moving on several fronts simultaneously: AI-driven protein and pathway design compressing design-build-test cycles; continuous and intensified fermentation displacing batch operation; cell-free systems removing the constraints of cell viability; and alternative feedstocks — C1 gases, lignocellulosics and captured CO₂ — reducing dependence on food crops.
The sector's record also warrants caution. Between 2019 and 2026 POET halted cellulosic production at Project Liberty, Clariant closed its Podari plant and exited biofuels, Fulcrum BioEnergy and Red Rock Biofuels entered bankruptcy without completing commercial production, both Enerkem sites failed, and Viridos filed for Chapter 11 after ExxonMobil ended a $350 million algae programme. No commercial biomass gasification-Fischer-Tropsch plant operates anywhere. Announced capacity consistently exceeds realised capacity, and forecasts should be read as contingent on a scale-up that has repeatedly proven harder than projected.
The Global Industrial Biomanufacturing Market 2027-2037 provides a comprehensive assessment of industrial biomanufacturing across its six commercial domains, combining technology analysis, market forecasts to 2037 and profiles of more than 1,000 companies. Industrial biomanufacturing has moved from a substitution play to a matter of industrial strategy, driven by decarbonisation targets, supply-chain security concerns and the emergence of AI-enabled biological design. This report examines what is genuinely commercial, what remains pre-commercial, and where announced capacity has failed to materialise. Coverage begins with production platforms — microbial fermentation, mammalian, plant and insect cell culture, transgenic systems and cell-free biomanufacturing — before addressing enabling technologies including synthetic biology, CRISPR-based strain engineering, continuous and intensified processing, downstream separation, and AI and robotics in bioprocess design.
Six market chapters then assess biopharmaceuticals, industrial enzymes, biofuels, bioplastics, biochemicals and bio-agritech. Each covers technology and materials analysis, market drivers, regulations, value chain, technology readiness, addressable market size, risks and opportunities, and global revenue forecasts segmented by product type, application and region. The report includes revenue and volume forecasts to 2037, capacity and consumption series for renewable diesel, biodiesel, bio-jet fuel, bioethanol, biomethane and bio-LNG, and detailed assessments of feedstock availability including waste lipids, lignocellulosics, C1 and C2 gases, and captured CO₂. More than 1,080 companies are profiled with descriptions, country of operation and website.
Contents
- Executive Summary — definition and scope, processes, key components, economic importance, colours of biotechnology, markets, AI and robotics, emerging technologies
- Production — microbial fermentation, mammalian cell culture, plant cell culture, insect cell culture, transgenic animals and plants, technologies, scale, mode of operation, host organisms
- Biopharmaceuticals — overview, technology analysis, market analysis, company profiles
- Industrial Enzymes (Biocatalysts) — overview, technology analysis, market analysis, company profiles
- Biofuels — overview, technology analysis, market analysis, company profiles
- Bioplastics — overview, technology analysis, market analysis, company profiles
- Biochemicals — overview, technology analysis, market analysis, company profiles
- Bio-Agritech — overview, technology analysis, market analysis, company profiles
Companies profiled include 3Bar Biologics, 3DBioFibR, 3M, 9Fiber, Inc., AbbVie, Absci Corp, Adaptive Symbiotic Technologies, ADBioplastics, Adjuvants Plus, Adriano di Marti/Desserto, Aduro Clean Technologies, Inc., Advanced Biochemical (Thailand) Co., Ltd., Aemetis, Inc., AEP Polymers, Aeropowder Limited, AFINGEN®, Afyren, AGAE Technologies LLC, Again Bio, AgBiome, Agilyx, Agra Energy, Agragene, AGRANA Staerke GmbH, Agrinos, Agrivida, Agrobiomics, AgroRenew, AgroSpheres, Ahlstrom-Munksjö Oyj, AI Proteins, Air Company, Aircela Inc, Alexion Pharmaceuticals, Algaeing, Algal Bio Co., Ltd., Algenesis Corporation, Algenie, Algenl, Algenol, Alginor ASA, Algix LLC, Allied Carbon Solutions, Allozymes, Alnylam Pharmaceuticals, Alpha Biofuels (Singapore) Pte Ltd, Alto Neuroscience, AM Green, Amano Enzyme Inc., Amatera, Amfora, Amgen, AmicaTerra, Aminoverse, Amphista Therapeutics, AmphiStar, Amply Discovery, AMSilk GmbH, An Phát Bioplastics, Ananas Anam Ltd., Andermatt Biocontrol, Andritz AG, Anellotech, Inc., Ankor Bioplastics Co., Ltd., Anodyne Chemistries, ANPOLY, Inc., Anqing He Xing Chemical Co., Ltd., Ansa Biotechnologies, Antheia, APChemi Pvt. Ltd., Apeiron Bioenergy, Aperam BioEnergia, Apexzymes, Aphea.Bio, Applied Bioplastics, Applied Research Associates, Inc. (ARA), Aqemia, Aquafil S.p.A., Aquapak Polymers Ltd, Arcadia Biosciences, Arcadia eFuels, Archer Daniel Midland Company (ADM), Arctic Biomaterials Oy, Ardra Bio, Arekapak GmbH, Arkema S.A, Arlanxeo, Arrow Greentech, Arysta LifeScience, Arzeda, Arzeda Corp., Asahi Kasei Chemicals Corporation, ASB Biodiesel Limited, Ascribe Bioscience, AstraZeneca, Atantares, Athos Therapeutics, Atlántica Agrícola, Atmonia, Atomwise, Attis Innovations, llc, Aurigene Pharmaceutical Services, AVA Biochem AG, Avalon BioEnergy, Avani Eco, Avantium B.V., Avicenna Biosciences, Avient Corporation, Avioxx, Axcelon Biopolymers Corporation, Ayas Renewables Inc., Azolla, Azotic Technologies, B-PREG, Balrampur Chini Mills, Bambooder Biobased Fibers B.V., Basecamp Research, BASF, BASF SE, Bast Fiber Technologies, Inc., Bayer CropScience, BBCA Biochemical & GALACTIC Lactic Acid Co., Ltd., Bcomp ltd., BDI-BioEnergy International GmbH, BEE Biofuel, Bee Vectoring Technologies, BeiGene, Benefuel Inc., BenevolentAI, Better Fibre Technologies, Betulium Oy, Beyond Leather Materials ApS, BigHat Biosciences, BigSis, Bio Fab NZ, BIO-FED, BIO-LUTIONS International AG, Bio-Oils, Bio2Materials Sp. z o.o., Bio2Oil ApS, BioAge Labs, Biobest, BioBetter, Biocatalysts Ltd., Bioceres Crop Solutions, Biocon, BioConsortia, BIOD Energy, BioEnz Technologies, Bioextrax AB, Biofiber Tech Sweden AB, Biofibre GmbH, Biofine Technology, LLC, Bioform Technologies, Biofy, BiogasClean A/S, Biogen, Biojet AS, Biokemik, Bioleather, Biolevel, Biolexis Therapeutics, Bioline AgroSciences, BIOLO, BioLogiQ, Inc., BioMap, Biomass Resin Holdings Co., Ltd., Biomatter, Biomatter Designs, Biome Bioplastics, Biome Makers, Bionema, BioNTech, BioPhero, Biophilica, BioPhy, Bioplastech Ltd, Bioplastix, Biopolax, Bioptimus SAS, BioSolutions, Biosyntia, Biotalys, BIOTEC GmbH & Co. KG, Biotecam, Biotechnology SL, Biotelliga, Biotensidion GmbH, Biotic Circular Technologies Ltd., Biotrem, Biotrop, Biovox, Bioweg, bitBiome, BlockTexx Pty Ltd., Bloom Biorenewables SA, BluCon Biotech GmbH, Blue BioFuels, Inc., Blue Ocean Closures, BlueAlp Technology, Bluepha Beijing Lanjing Microbiology Technology Co., Ltd., Bolt Threads, Bontera, Boreal Bioproducts, Borealis AG, Borregaard Chemcell, Bosk Bioproducts Inc., Botanical Solutions, Bowil Biotech Sp. z o.o., Braskem SA, Braven Environmental, LLC, Brightmark Energy, Brightseed, Bristol Myers Squibb, bse Methanol GmbH, BTG Bioliquids B.V., Bucha Bio, Inc., Burgo Group S.p.A., Buyo Bioplastic Ltd., Byogy Renewables, Inc., B’ZEOS, C-Zero Inc., C1 Green Chemicals AG, C16 Biosciences, Cambrium GmbH, Caphenia GmbH, CARAPAC Company, Carapace Biopolymers, Carbiolice, Carbios, Carbon Collect Limited, Carbon Crusher, Carbon Engineering Ltd., Carbon Infinity Limited, Carbon Recycling International, Carbon Sink LLC, Carbonade, CarbonBridge, Carbonwave, Carbyon BV, Cardia Bioplastics Ltd., Cardolite, Cargill, Cascade Biocatalysts, Cascade Biocatalysts, Inc., Cass Materials Pty Ltd, Cassandra Oil AB, Casterra Ag Ltd., Catalyxx, Cathay Industrial Biotech, Ltd., Celanese Corporation, Cellicon B.V., CellON, Celltrion, Cellucomp Ltd., Celluforce, Cellugy, Cellutech AB (Stora Enso), Celtic Renewables Ltd., Century Health Technology, Inc., Ceradis, Cereal Process Technologies (CPT), CERT Systems, Inc., Certis USA, CF Industries Holdings, Inc., CH-Bioforce Oy, ChainCraft, ChakraTech, Checkerspot, Inc., Chempolis Oy, Chestnut Bio Polymers, ChiralVision B.V., Chitelix, Chitose Bio Evolution Pte Ltd., Chongqing Bofei Biochemical Products Co., Ltd., Chuetsu Pulp & Paper Co., Ltd., Cibus, CIMV, CinderBio, Circa Group, Circla Nordic, Circular Systems, CJ Biomaterials, Inc., Clariant, Clariant AG, CleanJoule, Climeworks, CNF Biofuel AS, CO2BioClean, Coastgrass ApS, Codexis, COFCO Cooperation Ltd., Coffeeco Upcycle, Conagen, Concentric Agriculture, Concord Blue Engineering, Constructive Bio, Cool Planet Energy Systems, Corn Next, Corsair Group International, Corteva Agriscience, Corumat, Inc. and more....
1 EXECUTIVE SUMMARY 28
- 1.1 Definition and Scope of Industrial Biomanufacturing 28
- 1.2 Overview of Industrial Biomanufacturing Processes 29
- 1.3 Key Components of Industrial Biomanufacturing 31
- 1.4 Importance of Industrial Biomanufacturing in the Global Economy 32
- 1.5 Colours of Biotechnology 32
- 1.6 Markets 33
- 1.6.1 Biopharmaceuticals 33
- 1.6.2 Industrial Enzymes 34
- 1.6.3 Biofuels 34
- 1.6.4 Biomaterials and Bioplastics 35
- 1.6.5 Specialty Chemicals 36
- 1.6.6 Food and Beverage 36
- 1.6.7 Agriculture and Animal Health 37
- 1.6.8 Environmental Biotechnology 38
- 1.7 AI and Robotics in Biomanufacturing 39
- 1.8 Other Advanced and Emerging Technologies in Biomanufacturing 40
2 PRODUCTION 42
- 2.1 Microbial Fermentation 42
- 2.2 Mammalian Cell Culture 42
- 2.3 Plant Cell Culture 43
- 2.4 Insect Cell Culture 43
- 2.4.1 Overview 43
- 2.4.2 Cell lines 44
- 2.4.3 Process characteristics 44
- 2.4.4 Glycosylation 44
- 2.4.5 Commercial applications 44
- 2.4.6 Position within industrial biomanufacturing 45
- 2.5 Transgenic Animals 45
- 2.6 Transgenic Plants 46
- 2.7 Technologies 46
- 2.7.1 Upstream Processing 46
- 2.7.1.1 Cell Culture 46
- 2.7.1.1.1 Overview 46
- 2.7.1.1.2 Types of Cell Culture Systems 46
- 2.7.1.1.3 Factors Affecting Cell Culture Performance 47
- 2.7.1.1.4 Advances in Cell Culture Technology 48
- 2.7.1.1.4.1 Single-use systems 48
- 2.7.1.1.4.2 Process analytical technology (PAT) 48
- 2.7.1.1.4.3 Cell line development 48
- 2.7.1.1 Cell Culture 46
- 2.7.2 Fermentation 49
- 2.7.2.1 Overview 49
- 2.7.2.1.1 Types of Fermentation Processes 49
- 2.7.2.1.2 Factors Affecting Fermentation Performance 49
- 2.7.2.1.3 Advances in Fermentation Technology 50
- 2.7.2.1.3.1 High-cell-density fermentation 50
- 2.7.2.1.3.2 Continuous processing 50
- 2.7.2.1.3.3 Metabolic engineering 51
- 2.7.2.1.3.4 Synthetic biology applications 51
- 2.7.2.1.3.5 Cell-free systems 51
- 2.7.2.1.3.6 Continuous vs batch biomanufacturing 52
- 2.7.2.1 Overview 49
- 2.7.3 Downstream Processing 53
- 2.7.3.1 Purification 53
- 2.7.3.1.1 Overview 53
- 2.7.3.1.2 Types of Purification Methods 53
- 2.7.3.1.3 Factors Affecting Purification Performance 53
- 2.7.3.1.4 Advances in Purification Technology 54
- 2.7.3.1.4.1 Affinity chromatography 54
- 2.7.3.1.4.2 Membrane chromatography 54
- 2.7.3.1.4.3 Continuous chromatography 55
- 2.7.3.1.4.4 Downstream processing (DSP) improvements 55
- 2.7.3.1.4.5 Tangential flow filtration (TFF) in downstream bioprocessing 56
- 2.7.3.1 Purification 53
- 2.7.4 Formulation 57
- 2.7.4.1 Overview 57
- 2.7.4.1.1 Types of Formulation Methods 57
- 2.7.4.1.2 Factors Affecting Formulation Performance 57
- 2.7.4.1.3 Advances in Formulation Technology 58
- 2.7.4.1.3.1 Controlled release 58
- 2.7.4.1.3.2 Nanoparticle formulation 58
- 2.7.4.1.3.3 3D printing 58
- 2.7.4.1 Overview 57
- 2.7.5 Bioprocess Development 58
- 2.7.5.1 Scale-up 58
- 2.7.5.1.1 Overview 58
- 2.7.5.1.2 Factors Affecting Scale-up Performance 59
- 2.7.5.1.3 Scale-up Strategies 60
- 2.7.5.2 Optimization 60
- 2.7.5.2.1 Overview 60
- 2.7.5.2.2 Factors Affecting Optimization Performance 60
- 2.7.5.2.3 Optimization Strategies 61
- 2.7.5.2.4 Machine learning to improve biomanufacturing processes 62
- 2.7.5.2.5 Process intensification and high-cell-density fermentation 64
- 2.7.5.2.6 Hybrid biotechnological-chemical approaches 66
- 2.7.5.1 Scale-up 58
- 2.7.6 Analytical Methods 68
- 2.7.6.1 Quality Control 68
- 2.7.6.1.1 Overview 68
- 2.7.6.1.2 Types of Quality Control Tests 68
- 2.7.6.1.3 Factors Affecting Quality Control Performance 70
- 2.7.6.2 Characterization 70
- 2.7.6.2.1 Overview 70
- 2.7.6.2.2 Types of Characterization Methods 71
- 2.7.6.2.3 Factors Affecting Characterization Performance 72
- 2.7.6.1 Quality Control 68
- 2.7.7 Synthetic Biology Tools and Techniques 73
- 2.7.7.1 DNA synthesis 73
- 2.7.7.2 CRISPR-Cas9 systems 74
- 2.7.7.3 Protein/enzyme engineering 74
- 2.7.7.4 Computer-aided design 75
- 2.7.7.5 Strain construction and optimization 76
- 2.7.7.6 Robotics and automation 77
- 2.7.7.7 Artificial intelligence and machine learning 78
- 2.7.8 Alternative Feedstocks and Sustainability 79
- 2.7.8.1 C1 feedstocks: Metabolic pathways 79
- 2.7.8.2 C2 feedstocks 80
- 2.7.8.3 Lignocellulosic biomass feedstocks 81
- 2.7.8.4 Blue biotechnology feedstocks 82
- 2.7.8.5 Routes for carbon capture in biotechnology 83
- 2.7.1 Upstream Processing 46
- 2.8 Scale of Production 84
- 2.8.1 Laboratory Scale 84
- 2.8.1.1 Overview 84
- 2.8.1.2 Scale and Equipment 84
- 2.8.1.3 Advantages 85
- 2.8.1.4 Disadvantages 85
- 2.8.2 Pilot Scale 86
- 2.8.2.1 Overview 86
- 2.8.2.2 Scale and Equipment 86
- 2.8.2.3 Advantages 86
- 2.8.2.4 Disadvantages 87
- 2.8.3 Commercial Scale 87
- 2.8.3.1 Overview 87
- 2.8.3.2 Scale and Equipment 87
- 2.8.3.3 Advantages 88
- 2.8.3.4 Disadvantages 89
- 2.8.1 Laboratory Scale 84
- 2.9 Mode of Operation 89
- 2.9.1 Batch Production 89
- 2.9.1.1 Overview 89
- 2.9.1.2 Advantages 90
- 2.9.1.3 Disadvantages 90
- 2.9.1.4 Applications 91
- 2.9.2 Fed-batch Production 91
- 2.9.2.1 Overview 91
- 2.9.2.2 Advantages 91
- 2.9.2.3 Disadvantages 92
- 2.9.2.4 Applications 92
- 2.9.3 Continuous Production 92
- 2.9.3.1 Overview 92
- 2.9.3.2 Advantages 92
- 2.9.3.3 Disadvantages 93
- 2.9.3.4 Applications 93
- 2.9.3.5 Key fermentation parameter comparison 93
- 2.9.4 Cell factories for biomanufacturing 95
- 2.9.4.1 Range of organisms 96
- 2.9.4.2 Escherichia coli (E.coli) 97
- 2.9.4.3 Corynebacterium glutamicum (C. glutamicum) 98
- 2.9.4.4 Bacillus subtilis (B. subtilis) 99
- 2.9.4.5 Saccharomyces cerevisiae (S. cerevisiae) 100
- 2.9.4.6 Yarrowia lipolytica (Y. lipolytica) 101
- 2.9.4.7 Non-model organisms 101
- 2.9.5 Perfusion Culture 103
- 2.9.5.1 Overview 103
- 2.9.5.2 Advantages 103
- 2.9.5.3 Disadvantages 103
- 2.9.5.4 Applications 103
- 2.9.5.5 Perfusion bioreactors 104
- 2.9.6 Other Modes of Operation 105
- 2.9.6.1 Immobilized Cell Culture 105
- 2.9.6.1.1 Immobilized enzymes 105
- 2.9.6.1.2 Immobilized catalysts 106
- 2.9.6.2 Two-Stage Production 107
- 2.9.6.3 Hybrid Systems 107
- 2.9.6.1 Immobilized Cell Culture 105
- 2.9.1 Batch Production 89
- 2.10 Host Organisms 108
3 BIOPHARMACEUTICALS 110
- 3.1 Overview 110
- 3.2 Technology/materials analysis 110
- 3.2.1 Monoclonal Antibodies (mAbs) 110
- 3.2.2 Recombinant Proteins 111
- 3.2.3 Vaccines 111
- 3.2.4 Cell and Gene Therapies 112
- 3.2.5 Blood Factors 113
- 3.2.6 Tissue Engineering Products 113
- 3.2.7 Nucleic Acid Therapeutics 114
- 3.2.8 Peptide Therapeutics 114
- 3.2.9 Biosimilars and Biobetters 115
- 3.2.10 Nanobodies and Antibody Fragments 116
- 3.2.11 Synthetic biology 116
- 3.2.11.1 Metabolic engineering 117
- 3.2.11.1.1 DNA synthesis 117
- 3.2.11.1.2 CRISPR 118
- 3.2.11.1.2.1 CRISPR/Cas9-modified biosynthetic pathways 118
- 3.2.11.2 Protein/Enzyme Engineering 119
- 3.2.11.3 Strain construction and optimization 120
- 3.2.11.4 Synthetic biology and metabolic engineering 121
- 3.2.11.5 Smart bioprocessing 121
- 3.2.11.6 Cell-free systems 122
- 3.2.11.7 Chassis organisms 124
- 3.2.11.8 Biomimetics 125
- 3.2.11.9 Sustainable materials 126
- 3.2.11.10 Robotics and automation 126
- 3.2.11.10.1 Robotic cloud laboratories 127
- 3.2.11.10.2 Automating organism design 127
- 3.2.11.10.3 Artificial intelligence and machine learning 127
- 3.2.11.11 Fermentation Processes 128
- 3.2.11.1 Metabolic engineering 117
- 3.2.12 Generative Biology 128
- 3.2.12.1 Generative Adversarial Networks (GANs) 130
- 3.2.12.1.1 Variational Autoencoders (VAEs) 130
- 3.2.12.1.2 Normalizing Flows 130
- 3.2.12.1.3 Autoregressive Models 130
- 3.2.12.1.4 Evolutionary Generative Models 131
- 3.2.12.2 Design Optimization 131
- 3.2.12.2.1 Evolutionary Algorithms (e.g., Genetic Algorithms, Evolutionary Strategies) 131
- 3.2.12.2.1.1 Genetic Algorithms (GAs) 131
- 3.2.12.2.1.2 Evolutionary Strategies (ES) 131
- 3.2.12.2.2 Reinforcement Learning 132
- 3.2.12.2.3 Multi-Objective Optimization 132
- 3.2.12.2.4 Bayesian Optimization 132
- 3.2.12.2.1 Evolutionary Algorithms (e.g., Genetic Algorithms, Evolutionary Strategies) 131
- 3.2.12.3 Computational Biology 133
- 3.2.12.3.1 Molecular Dynamics Simulations 133
- 3.2.12.3.2 Quantum Mechanical Calculations 134
- 3.2.12.3.3 Systems Biology Modeling 134
- 3.2.12.3.4 Metabolic Engineering Modeling 135
- 3.2.12.4 Data-Driven Approaches 135
- 3.2.12.4.1 Machine Learning 136
- 3.2.12.4.2 Graph Neural Networks 136
- 3.2.12.4.3 Unsupervised Learning 136
- 3.2.12.4.4 Active Learning and Bayesian Optimization 137
- 3.2.12.5 Agent-Based Modeling 137
- 3.2.12.6 Hybrid Approaches 138
- 3.2.12.1 Generative Adversarial Networks (GANs) 130
- 3.3 Market analysis 139
- 3.3.1 Key players and competitive landscape 139
- 3.3.2 Market Growth Drivers and Trends 140
- 3.3.3 Regulations 141
- 3.3.4 Value chain 142
- 3.3.5 Future outlook 143
- 3.3.6 Technology Readiness Level (TRL) 143
- 3.3.7 Addressable Market Size 145
- 3.3.8 Risks and Opportunities 145
- 3.3.9 Global revenues 147
- 3.3.9.1 By application market 147
- 3.3.9.2 By regional market 148
- 3.4 Company profiles 148
4 INDUSTRIAL ENZYMES (BIOCATALYSTS) 170
- 4.1 Overview 170
- 4.1.1 Bio-manufactured enzymes 170
- 4.2 Technology/materials analysis 171
- 4.2.1 Detergent Enzymes 171
- 4.2.2 Food Processing Enzymes 172
- 4.2.3 Textile Processing Enzymes 172
- 4.2.4 Paper and Pulp Processing Enzymes 173
- 4.2.5 Leather Processing Enzymes 173
- 4.2.6 Biofuel Production Enzymes 174
- 4.2.6.1 Enzymes for lignocellulosic derived bioethanol 174
- 4.2.6.2 Cellulases for lignocellulosic bioethanol 175
- 4.2.6.3 Hemicellulases and synergistic enzyme cocktails 176
- 4.2.6.4 Thermostable and extremophilic enzymes 177
- 4.2.6.5 Cost-performance metrics for thermostable enzymes 178
- 4.2.7 Animal Feed Enzymes 179
- 4.2.8 Pharmaceutical and Diagnostic Enzymes 180
- 4.2.9 Waste Management and Bioremediation Enzymes 180
- 4.2.9.1 Enzymes for plastics recycling 181
- 4.2.9.2 Enzymatic depolymerization 182
- 4.2.9.3 Challenges in enzymatic depolymerization 183
- 4.2.10 Agriculture and Crop Improvement Enzymes 183
- 4.2.11 Enzymes for Decarbonization and CO₂ Utilization 185
- 4.2.11.1 Carbonic anhydrase in CO₂ capture technologies 187
- 4.2.11.2 Formate dehydrogenase and CO₂-to-chemicals pathways 188
- 4.2.11.3 Selected enzymatic approaches to CO2 capture and conversion 189
- 4.3 Market analysis 190
- 4.3.1 Key players and competitive landscape 190
- 4.3.2 Market Growth Drivers and Trends 191
- 4.3.3 Technology challenges and opportunities for industrial enzymes 192
- 4.3.4 Economic competitiveness of enzymatic processing 194
- 4.3.5 Regulations 194
- 4.3.6 Value chain 195
- 4.3.7 Future outlook 196
- 4.3.8 Technology Readiness Level (TRL) 197
- 4.3.9 Addressable Market Size 197
- 4.3.10 Risks and Opportunities 198
- 4.3.11 Global revenues 199
- 4.3.11.1 By application market 199
- 4.3.11.2 By regional market 199
- 4.4 Company profiles 200
5 BIOFUELS 213
- 5.1 Overview 213
- 5.2 Technology/materials analysis 215
- 5.2.1 Role in the circular economy 215
- 5.2.2 The global biofuels market 217
- 5.2.3 Feedstocks 217
- 5.2.3.1 First-generation (1-G) 218
- 5.2.3.2 Second-generation (2-G) 219
- 5.2.3.2.1 Lignocellulosic wastes and residues 220
- 5.2.3.2.2 Biorefinery lignin 222
- 5.2.3.3 Third-generation (3-G) 226
- 5.2.3.3.1 Algal biofuels 226
- 5.2.3.3.1.1 Properties 227
- 5.2.3.3.1.2 Advantages 227
- 5.2.3.3.1 Algal biofuels 226
- 5.2.3.4 Fourth-generation (4-G) 228
- 5.2.3.5 Advantages and disadvantages, by generation 229
- 5.2.4 Bioethanol 230
- 5.2.4.1 First-generation bioethanol (from sugars and starches) 230
- 5.2.4.2 Second-generation bioethanol (from lignocellulosic biomass) 230
- 5.2.4.3 Third-generation bioethanol (from algae) 231
- 5.2.5 Biodiesel 231
- 5.2.5.1 Biodiesel by generation 231
- 5.2.5.2 Production of biodiesel and other biofuels 232
- 5.2.5.2.1 Pyrolysis of biomass 233
- 5.2.5.2.2 Vegetable oil transesterification 236
- 5.2.5.2.3 Vegetable oil hydrogenation (HVO) 237
- 5.2.5.2.3.1 Production process 237
- 5.2.5.2.4 Biodiesel from tall oil 239
- 5.2.5.2.5 Fischer-Tropsch BioDiesel 239
- 5.2.5.2.6 Hydrothermal liquefaction of biomass 242
- 5.2.5.2.7 CO2 capture and Fischer-Tropsch (FT) 242
- 5.2.5.2.8 Dymethyl ether (DME) 243
- 5.2.5.3 Prices 243
- 5.2.5.4 Global production and consumption 244
- 5.2.6 Biogas 245
- 5.2.6.1 Feedstocks 247
- 5.2.6.2 Biomethane 248
- 5.2.6.2.1 Production pathways 250
- 5.2.6.2.1.1 Landfill gas recovery 250
- 5.2.6.2.1.2 Anaerobic digestion 250
- 5.2.6.2.1.3 Thermal gasification 251
- 5.2.6.2.1 Production pathways 250
- 5.2.6.3 Global production 252
- 5.2.6.4 Prices 252
- 5.2.6.4.1 Raw Biogas 252
- 5.2.6.4.2 Upgraded Biomethane 253
- 5.2.6.5 Bio-LNG 253
- 5.2.6.5.1 Markets 253
- 5.2.6.5.1.1 Trucks 253
- 5.2.6.5.1.2 Marine 253
- 5.2.6.5.2 Plants 253
- 5.2.6.5.1 Markets 253
- 5.2.6.6 bio-CNG (compressed natural gas derived from biogas) 254
- 5.2.6.7 Carbon capture from biogas 254
- 5.2.6.8 Biosyngas 255
- 5.2.6.8.1 Production 255
- 5.2.6.8.2 Prices 256
- 5.2.7 Biobutanol 256
- 5.2.7.1 Production 258
- 5.2.7.2 Prices 258
- 5.2.8 Biohydrogen 259
- 5.2.8.1 Description 259
- 5.2.8.1.1 Dark fermentation 259
- 5.2.8.1.2 Photofermentation 260
- 5.2.8.1.3 Biophotolysis (direct and indirect) 260
- 5.2.8.1.3.1 Direct Biophotolysis: 260
- 5.2.8.1.3.2 Indirect Biophotolysis: 261
- 5.2.8.2 Production of biohydrogen from biomass 262
- 5.2.8.2.1 Biological Conversion Routes 262
- 5.2.8.2.1.1 Bio-photochemical Reaction 262
- 5.2.8.2.1.2 Fermentation and Anaerobic Digestion 263
- 5.2.8.2.2 Thermochemical conversion routes 263
- 5.2.8.2.2.1 Biomass Gasification 263
- 5.2.8.2.2.2 Biomass Pyrolysis 263
- 5.2.8.2.2.3 Biomethane Reforming 264
- 5.2.8.2.1 Biological Conversion Routes 262
- 5.2.8.3 Applications 264
- 5.2.8.4 Prices 265
- 5.2.8.1 Description 259
- 5.2.9 Biomethanol 265
- 5.2.9.1 Gasification-based biomethanol 265
- 5.2.9.2 Biosynthesis-based biomethanol 266
- 5.2.9.3 Methanol-to gasoline technology 266
- 5.2.9.3.1 Production processes 267
- 5.2.9.3.1.1 Anaerobic digestion 268
- 5.2.9.3.1.2 Biomass gasification 268
- 5.2.9.3.1.3 Power to Methane 269
- 5.2.9.3.1 Production processes 267
- 5.2.10 Bio-oil and Biochar 269
- 5.2.10.1 Pyrolysis-based bio-oil 270
- 5.2.10.2 Hydrothermal liquefaction-based bio-oil 271
- 5.2.10.3 Biochar from pyrolysis and gasification processes 271
- 5.2.10.4 Advantages of bio-oils 273
- 5.2.10.5 Production 274
- 5.2.10.5.1 Fast Pyrolysis 274
- 5.2.10.5.2 Costs of production 274
- 5.2.10.5.3 Upgrading 274
- 5.2.10.6 Applications 275
- 5.2.10.7 Bio-oil producers 276
- 5.2.10.8 Prices 276
- 5.2.10.8.1 Biochar co-product economics 277
- 5.2.10.8.2 Biochar in anaerobic digestion 278
- 5.2.11 Renewable Diesel and Jet Fuel 278
- 5.2.11.1 Renewable diesel 278
- 5.2.11.1.1 Production 278
- 5.2.11.1.2 Global consumption 279
- 5.2.11.1.3 Prices 280
- 5.2.11.2 Bio-aviation fuel (bio-jet fuel, sustainable aviation fuel, renewable jet fuel or aviation biofuel) 280
- 5.2.11.2.1 Description 280
- 5.2.11.2.2 SWOT analysis 282
- 5.2.11.2.3 Global production and consumption 283
- 5.2.11.2.4 Production pathways 283
- 5.2.11.2.5 Prices 284
- 5.2.11.2.6 Bio-aviation fuel production capacities 285
- 5.2.11.2.7 Challenges 285
- 5.2.11.2.8 Global consumption 286
- 5.2.11.1 Renewable diesel 278
- 5.2.12 Algal biofuels 286
- 5.2.12.1 Conversion pathways 286
- 5.2.12.2 SWOT analysis 287
- 5.2.12.3 Production 288
- 5.2.12.4 Market challenges 289
- 5.2.12.5 Prices 290
- 5.2.12.6 Producers 291
- 5.3 Market analysis 292
- 5.3.1 Key players and competitive landscape 292
- 5.3.2 Market Growth Drivers and Trends 295
- 5.3.3 Regulations 295
- 5.3.4 Value chain 296
- 5.3.5 Future outlook 297
- 5.3.6 Technology Readiness Level (TRL) 299
- 5.3.7 Addressable Market Size 300
- 5.3.8 Risks and Opportunities 301
- 5.3.9 Global revenues 301
- 5.3.9.1 By biofuel type 301
- 5.3.9.2 Applications Market 302
- 5.3.9.3 By regional market 302
- 5.4 Company profiles 302
6 BIOPLASTICS 351
- 6.1 Overview 352
- 6.2 Technology/materials analysis 353
- 6.2.1 Polylactic acid (PLA) 353
- 6.2.1.1 NatureWorks: second global manufacturing site, Thailand 354
- 6.2.1.2 PLA and PEF product developments (2026) 354
- 6.2.1.3 Henan Techuang Biotechnology 354
- 6.2.2 Polyhydroxyalkanoates (PHAs) 355
- 6.2.2.1 Types 356
- 6.2.2.2 Polyhydroxybutyrate (PHB) 359
- 6.2.2.3 Polyhydroxyvalerate (PHV) 360
- 6.2.2.4 Ourobio: PHAs and pigments from waste streams 360
- 6.2.2.5 Shellworks: Vivomer PHA packaging 360
- 6.2.3 Bio-based polyethylene (PE) 361
- 6.2.4 Bio-based polyethylene terephthalate (PET) 361
- 6.2.5 Bio-based polyurethanes (PUs) 362
- 6.2.6 Starch-based plastics 363
- 6.2.7 Cellulose-based plastics 364
- 6.2.7.1 Ecovative Forager: mycelium hides and foams 364
- 6.2.1 Polylactic acid (PLA) 353
- 6.3 Market analysis 365
- 6.3.1 Key players and competitive landscape 365
- 6.3.2 Market Growth Drivers and Trends 366
- 6.3.2.1 European biobased lead markets and demand-side measures 366
- 6.3.3 Regulations 366
- 6.3.4 Value chain 367
- 6.3.5 Future outlook 368
- 6.3.5.1 Effect of 2026 developments on the outlook 369
- 6.3.6 Technology Readiness Level (TRL) 369
- 6.3.7 Addressable Market Size 371
- 6.3.8 Risks and Opportunities 371
- 6.3.9 Global revenues 372
- 6.3.9.1 By type 372
- 6.3.9.2 By application market 372
- 6.3.9.3 By regional market 373
- 6.4 Company profiles 373
7 BIOCHEMICALS 517
- 7.1 Overview 517
- 7.2 Technology/materials analysis 519
- 7.2.1 Organic acids 522
- 7.2.1.1 Lactic acid 522
- 7.2.1.1.1 D-lactic acid 522
- 7.2.1.1.2 L-lactic acid 522
- 7.2.1.2 Succinic acid 523
- 7.2.1.3 Itaconic acid 524
- 7.2.1.4 Citric acid 525
- 7.2.1.5 Acetic acid 525
- 7.2.1.6 Malonic acid 526
- 7.2.1.1 Lactic acid 522
- 7.2.2 Amino acids 526
- 7.2.2.1 Glutamic acid 526
- 7.2.2.2 Lysine 527
- 7.2.2.3 Threonine 528
- 7.2.2.4 Methionine 529
- 7.2.2.5 Vitamins produced using biotechnology 529
- 7.2.2.5.1 Vitamin B2 (Riboflavin) 530
- 7.2.2.5.2 Vitamin B12 (Cobalamin) 530
- 7.2.2.5.3 Vitamin C (Ascorbic Acid) 531
- 7.2.2.5.4 Vitamin B7 (Biotin) 532
- 7.2.2.5.5 Vitamin B3 (Niacin / Nicotinic Acid) 532
- 7.2.2.5.6 Vitamin B9 (Folic Acid / Folate) 533
- 7.2.3 Alcohols 534
- 7.2.3.1 Ethanol 534
- 7.2.3.2 Butanol 534
- 7.2.3.3 Isobutanol 535
- 7.2.3.4 Propanediol 536
- 7.2.3.5 Catalyxx: commercial-scale renewable alcohols, Sines, Portugal 537
- 7.2.4 Surfactants 537
- 7.2.4.1 Biosurfactants (e.g., rhamnolipids, sophorolipids) 537
- 7.2.4.1.1 Rhamnolipids 538
- 7.2.4.1.2 Sophorolipids 539
- 7.2.4.1.3 Mannosylerythritol lipids (MELs) 540
- 7.2.4.1.4 Cellobiose lipids 541
- 7.2.4.1.5 Designer glycolipids and lipopeptides via synthetic biology 542
- 7.2.4.2 Alkyl polyglucosides (APGs) 543
- 7.2.4.1 Biosurfactants (e.g., rhamnolipids, sophorolipids) 537
- 7.2.5 Solvents 543
- 7.2.5.1 Ethyl lactate 543
- 7.2.5.2 Dimethyl carbonate 544
- 7.2.5.3 Glycerol 545
- 7.2.6 Flavours and fragrances 545
- 7.2.6.1 Vanillin 545
- 7.2.6.2 Nootkatone 546
- 7.2.6.3 Limonene 547
- 7.2.6.4 Bio-manufactured fragrances and aromatics 548
- 7.2.6.5 Biotech-derived fragrance precursors 549
- 7.2.6.6 Ambroxan 550
- 7.2.6.7 Flavour enhancers 551
- 7.2.6.8 Disodium Inosinate (IMP) 552
- 7.2.6.9 Disodium Guanylate (GMP) 553
- 7.2.6.10 Monatin 554
- 7.2.7 Bio-based monomers and intermediates 554
- 7.2.7.1 Succinic acid 554
- 7.2.7.2 1,4-Butanediol (BDO) 555
- 7.2.7.3 Isoprene 556
- 7.2.7.4 Ethylene 556
- 7.2.7.5 Propylene 557
- 7.2.7.6 Adipic acid 558
- 7.2.7.7 Acrylic acid 559
- 7.2.7.8 Sebacic acid 559
- 7.2.7.9 Genomatica (Geno) acquired by Again 560
- 7.2.7.10 Hyosung TNC: Bio-BDO production in Vietnam 560
- 7.2.7.11 17Cicada: FDCA from mixed waste 561
- 7.2.7.12 C12: Dodecanedioic acid (DDDA) 561
- 7.2.7.13 1,5-Pentanediamine (PDA) 561
- 7.2.8 Bio-based polymers 562
- 7.2.8.1 Polybutylene succinate (PBS) 562
- 7.2.8.2 Polyamides (nylons) 563
- 7.2.8.3 Polyethylene furanoate (PEF) 563
- 7.2.8.4 Polytrimethylene terephthalate (PTT) 564
- 7.2.8.5 Polyethylene isosorbide terephthalate (PEIT) 566
- 7.2.9 Bio-based composites and blends 567
- 7.2.9.1 Wood-plastic composites (WPCs) 567
- 7.2.9.2 Biofiller-reinforced plastics 568
- 7.2.9.3 Biofiber-reinforced plastics 568
- 7.2.9.4 Polymer blends with bio-based components 570
- 7.2.10 Beauty and Personal Care Chemicals 571
- 7.2.10.1 Hyaluronic acid production 571
- 7.2.10.2 Squalene and Squalane alternatives 572
- 7.2.10.3 Collagen 573
- 7.2.10.4 Bio-based UV filters and photoprotective compounds 574
- 7.2.10.5 Melanin 575
- 7.2.10.6 Emollients 576
- 7.2.11 Waste 577
- 7.2.11.1 Food waste 577
- 7.2.11.2 Agricultural waste 578
- 7.2.11.3 Forestry waste 578
- 7.2.11.4 Aquaculture/fishing waste 579
- 7.2.11.5 Municipal solid waste 579
- 7.2.11.6 Industrial waste 580
- 7.2.11.7 Waste oils 580
- 7.2.11.8 Recycling and circularity developments (2026) 581
- 7.2.11.9 Biomason: biocement 581
- 7.2.12 Microbial and mineral sources 581
- 7.2.12.1 Microalgae 581
- 7.2.12.2 Macroalgae 582
- 7.2.12.3 Cyanobacteria 582
- 7.2.12.4 Mineral sources 583
- 7.2.13 Other Bio-manufactured Products 584
- 7.2.13.1 Cement alternatives from biomanufacturing 584
- 7.2.13.2 Precision fermentation products 585
- 7.2.1 Organic acids 522
- 7.3 Market analysis 586
- 7.3.1 Key players and competitive landscape 586
- 7.3.1.1 Company landscape in specialty chemicals biotechnology 587
- 7.3.1.2 Bio-manufactured beauty ingredient production capacities 588
- 7.3.2 Market Growth Drivers and Trends 589
- 7.3.2.1 Trends and drivers in biotechnology 589
- 7.3.2.2 Government support of biotechnology 590
- 7.3.2.3 Carbon taxes 591
- 7.3.3 Regulations 592
- 7.3.4 Value chain 593
- 7.3.4.1 Economic viability factors 593
- 7.3.4.2 Effect of feedstock prices 594
- 7.3.4.3 Scale-up effects on cost 595
- 7.3.5 Future outlook 596
- 7.3.6 Technology Readiness Level (TRL) 597
- 7.3.7 Addressable Market Size 598
- 7.3.8 Risks and Opportunities 599
- 7.3.9 Major market challenges 599
- 7.3.10 Technical challenges 600
- 7.3.11 Global revenues 601
- 7.3.11.1 By type 601
- 7.3.11.2 By application market 602
- 7.3.11.3 By regional market 602
- 7.3.1 Key players and competitive landscape 586
- 7.4 Company profiles 603
8 BIO-AGRITECH 622
- 8.1 Overview 622
- 8.2 Technology/materials analysis 623
- 8.2.1 Biopesticides 623
- 8.2.1.1 Semiochemical 624
- 8.2.1.2 Macrobial Biological Control Agents 624
- 8.2.1.3 Microbial pesticides 627
- 8.2.1.4 Biochemical pesticides 628
- 8.2.1.5 Plant-incorporated protectants (PIPs) 628
- 8.2.2 Biofertilizers 629
- 8.2.3 Biostimulants 630
- 8.2.3.1 Microbial biostimulants 630
- 8.2.3.1.1 Nitrogen Fixation 632
- 8.2.3.1.2 Formulation Challenges 634
- 8.2.3.2 Natural Product Biostimulants 634
- 8.2.3.3 Manipulating the Microbiome 637
- 8.2.3.4 Synthetic Biology 638
- 8.2.3.5 Non-microbial biostimulants 639
- 8.2.3.1 Microbial biostimulants 630
- 8.2.4 Agricultural Enzymes 640
- 8.2.4.1 Types of Agricultural Enzymes 640
- 8.2.1 Biopesticides 623
- 8.3 Market analysis 641
- 8.3.1 Key players and competitive landscape 641
- 8.3.2 Market Growth Drivers and Trends 642
- 8.3.3 Regulations 643
- 8.3.4 Value chain 643
- 8.3.5 Future outlook 644
- 8.3.6 Addressable Market Size 645
- 8.3.7 Risks and Opportunities 645
- 8.3.8 Global revenues 646
- 8.3.8.1 By application market 646
- 8.3.8.2 By regional market 647
- 8.4 Company profiles 647
9 RESEARCH METHODOLOGY 671
10 REFERENCES 671
List of Tables
- Table 1. Biomanufacturing revolutions and representative products. 28
- Table 2. Industrial Biomanufacturing categories. 29
- Table 3. Overview of Biomanufacturing Processes. 30
- Table 4. Continuous vs batch biomanufacturing 31
- Table 5. Key Components of Industrial Biomanufacturing. 31
- Table 6. Colours of biotechnology. 33
- Table 7. AI and Robotics Applications in Biomanufacturing 39
- Table 8. Advanced Technologies in Biomanufacturing Applications. 41
- Table 9. Types of Cell Culture Systems. 47
- Table 10. Factors Affecting Cell Culture Performance. 48
- Table 11. Types of Fermentation Processes. 49
- Table 12. Factors Affecting Fermentation Performance. 50
- Table 13. Advances in Fermentation Technology. 50
- Table 14. Continuous vs Batch Biomanufacturing Comparison. 52
- Table 15. Types of Purification Methods in Downstream Processing. 53
- Table 16. Factors Affecting Purification Performance. 53
- Table 17. Advances in Purification Technology. 54
- Table 18. Downstream Processing Technology Improvements. 56
- Table 19. TFF Applications in Downstream Processing. 56
- Table 20. Common formulation methods used in biomanufacturing. 57
- Table 21. Factors Affecting Formulation Performance. 57
- Table 22. Advances in Formulation Technology. 58
- Table 23. Factors Affecting Scale-up Performance in Biomanufacturing. 59
- Table 24. Scale-up Strategies in Biomanufacturing. 60
- Table 25. Factors Affecting Optimization Performance in Biomanufacturing. 61
- Table 26. Optimization Strategies in Biomanufacturing. 61
- Table 27. Machine Learning Applications in Biomanufacturing 63
- Table 28. High-Cell-Density Fermentation Parameters and Targets. 64
- Table 29. Hybrid Biotechnological-Chemical Process Applications. 66
- Table 30. Types of Quality Control Tests in Biomanufacturing. 68
- Table 31. Factors Affecting Quality Control Performance in Biomanufacturing 70
- Table 32. Types of Characterization Methods in Biomanufacturing. 71
- Table 33. Factors Affecting Characterization Performance in Biomanufacturing 72
- Table 34. DNA Synthesis Technologies and Capabilities. 73
- Table 35. CRISPR-Cas9 Applications in Biomanufacturing. 74
- Table 36. Protein Engineering Strategies and Applications. 75
- Table 37. Computer-Aided Design Tools in Biotechnology. 76
- Table 38. Strain Engineering Strategies and Targets. 77
- Table 39. Automation Applications in Biotechnology. 78
- Table 40. AI/ML Applications in Biomanufacturing Systems. 79
- Table 41. C1 Feedstock Utilization Pathways and Characteristics. 80
- Table 42. C2 Feedstock Processing and Applications. 80
- Table 43. Lignocellulosic Biomass Processing Technologies. 81
- Table 44. Blue Biotechnology Feedstock Characteristics and Applications. 82
- Table 45. Carbon Capture and Utilization Pathways in Biotechnology. 84
- Table 46. Key fermentation parameters in batch vs continuous biomanufacturing processes. 90
- Table 47. Key fermentation parameter comparison 93
- Table 48. Major microbial cell factories used in industrial biomanufacturing. 95
- Table 49. Organism Categories and Production Capabilities. 96
- Table 50. E. coli Characteristics for Biomanufacturing Applications. 97
- Table 51. C. glutamicum Production Capabilities and Characteristics. 98
- Table 52. B. subtilis Production Systems and Applications. 99
- Table 53. S. cerevisiae Capabilities and Industrial Applications. 100
- Table 54. Y. lipolytica Production Capabilities and Process Parameters. 101
- Table 55. Non-Model Organisms and Specialized Applications. 102
- Table 56. Perfusion Bioreactor Technologies and Performance. 104
- Table 57. Enzyme Immobilization Methods and Characteristics. 106
- Table 58. Immobilized Catalyst Systems and Applications. 107
- Table 59. Comparison of Modes of Operation. 108
- Table 60. Host organisms commonly used in biomanufacturing. 108
- Table 61. Types of biopharmaceuticals. 110
- Table 62. Types of Monoclonal Antibodies. 111
- Table 63. Types of Recombinant Proteins. 111
- Table 64. Types of biopharma vaccines. 112
- Table 65. Types of Cell and Gene Therapies 112
- Table 66. Types of Blood Factors. 113
- Table 67. Types of Tissue Engineering Products. 113
- Table 68. Types of Nucleic Acid Therapeutics. 114
- Table 69. Types of Peptide Therapeutics. 115
- Table 70. Types of Biosimilars and Biobetters. 115
- Table 71. Types of Nanobodies and Antibody Fragments. 116
- Table 72. Types of Synthetic Biology Applications in Biopharmaceuticals. 116
- Table 73. Engineered proteins in industrial applications. 120
- Table 74. Cell-free versus cell-based systems 123
- Table 75. White biotechnology fermentation processes. 128
- Table 76. Key players in biopharmaceuticals. 139
- Table 77. Market Growth Drivers and Trends in Biopharmaceuticals. 140
- Table 78. Biopharmaceuticals Regulations. 141
- Table 79. Value chain: Biopharmaceuticals. 142
- Table 80. Technology Readiness Level (TRL): Biopharmaceuticals. 143
- Table 81. Addressable market size for biopharmaceuticals. 145
- Table 82. Risks and Opportunities in biopharmaceuticals. 145
- Table 83. Global revenues for biopharmaceuticals, by applications market (2020-2037), billions USD. 147
- Table 84. Global revenues for biopharmaceuticals, by regional market (2020-2037), billions USD. 148
- Table 85. Biopharmaceuticals company profiles. 148
- Table 86. Types of industrial enzymes. 170
- Table 87. Types of Detergent Enzymes. 171
- Table 88. Types of Food Processing Enzymes 172
- Table 89. Types of Textile Processing Enzymes. 172
- Table 90. Types of Paper and Pulp Processing Enzymes. 173
- Table 91. Types of Leather Processing Enzymes. 173
- Table 92. Types of Biofuel Production Enzymes. 174
- Table 93. Lignocellulosic Enzyme Systems and Performance. 175
- Table 94. Cellulase Component Functions and Characteristics. 176
- Table 95. Hemicellulase Systems and Substrate Specificity. 177
- Table 96. Thermostable Enzyme Sources and Characteristics. 178
- Table 97. Thermostable Enzyme Economic Analysis Framework. 179
- Table 98. Types of Animal Feed Enzymes. 179
- Table 99. Types of Pharmaceutical and Diagnostic Enzymes. 180
- Table 100. Types of Waste Management and Bioremediation Enzymes. 180
- Table 101. Enzymes for Plastics Recycling Applications. 182
- Table 102. Challenges in Enzymatic Depolymerization. 183
- Table 103. Types of Agriculture and Crop Improvement Enzymes. 184
- Table 104. Comparison of enzyme types. 184
- Table 105. Enzymes for Decarbonization and CO₂ Utilization. 186
- Table 106. Carbonic Anhydrase Applications in CO₂ Capture. 188
- Table 107. Formate Dehydrogenase Systems for CO₂ Conversion. 189
- Table 108. Enzymatic CO₂ Capture and Conversion Technologies. 190
- Table 109. Key players in industrial enzymes. 190
- Table 110. Market Growth Drivers and Trends in industrial enzymes. 191
- Table 111. Technology Challenges and Opportunities for Industrial Enzymes. 192
- Table 112. Industrial enzymes Regulations. 194
- Table 113. Value chain: Industrial enzymes. 195
- Table 114. Technology Readiness Level (TRL): Biocatalysts. 197
- Table 115. Addressable market size for industrial enzymes. 198
- Table 116. Risks and Opportunities in industrial enzymes. 198
- Table 117. Global revenues for industrial enzymes, by applications market (2020-2037), billions USD. 199
- Table 118. Global revenues for industrial enzymes, by regional market (2020-2037), billions USD. 199
- Table 119. Industrial Enzymes Company Profiles. 200
- Table 120. Types of biofuel, by generation. 213
- Table 121. Comparison of biofuels. 216
- Table 122. Classification of biomass feedstock. 217
- Table 123. Biorefinery feedstocks. 218
- Table 124. Feedstock conversion pathways. 218
- Table 125. First-Generation Feedstocks. 218
- Table 126. Lignocellulosic ethanol plants and capacities. 221
- Table 127. Comparison of pulping and biorefinery lignins. 222
- Table 128. Commercial and pre-commercial biorefinery lignin production facilities and processes 222
- Table 129. Operating and planned lignocellulosic biorefineries and industrial flue gas-to-ethanol. 224
- Table 130. Properties of microalgae and macroalgae. 227
- Table 131. Yield of algae and other biodiesel crops. 228
- Table 132. Advantages and disadvantages of biofuels, by generation. 229
- Table 133. Biodiesel by generation. 231
- Table 134. Biodiesel production techniques. 232
- Table 135. Summary of pyrolysis technique under different operating conditions. 233
- Table 136. Biomass materials and their bio-oil yield. 235
- Table 137. Biofuel production cost from the biomass pyrolysis process. 236
- Table 138. Properties of vegetable oils in comparison to diesel. 237
- Table 139. Main producers of HVO and capacities. 238
- Table 140. Commercial development of BtL processes 240
- Table 141. Pilot or demo projects for biomass to liquid (BtL) processes. 241
- Table 142.Biodiesel (B20) average prices, current and historical, USD/litre. 243
- Table 143. Global biodiesel consumption, 2010–2037 (M litres/year) 244
- Table 144. Biogas and biomethane feedstock 247
- Table 145. Existing and planned bio-LNG production plants. 253
- Table 146. Methods for capturing carbon dioxide from biogas. 254
- Table 147. Total syngas market by product 255
- Table 148. Biosyngas price ranges by application: 256
- Table 149. Comparison of different Bio-H2 production pathways. 262
- Table 150. Markets and applications for biohydrogen. 264
- Table 151. Comparison of biogas, biomethane and natural gas. 268
- Table 152. Summary of applications of biochar in energy. 272
- Table 153. Typical composition and physicochemical properties reported for bio-oils and heavy petroleum-derived oils. 273
- Table 154. Properties and characteristics of pyrolysis liquids derived from biomass versus a fuel oil. 273
- Table 155. Main techniques used to upgrade bio-oil into higher-quality fuels. 275
- Table 156. Markets and applications for bio-oil. 275
- Table 157. Bio-oil producers. 276
- Table 158. Global renewable diesel consumption, 2010-2037 (M litres/year). 279
- Table 159. Renewable diesel price ranges 280
- Table 160. Advantages and disadvantages of Bio-aviation fuel. 281
- Table 161. Production pathways for Bio-aviation fuel. 284
- Table 162. Current and announced Bio-aviation fuel facilities and capacities. 285
- Table 163. Global bio-jet fuel consumption, 2019–2037 (million litres/year) 286
- Table 164. production cost estimates and projections 290
- Table 165. Algae-derived biofuel producers. 291
- Table 166. Key players in biofuels. 292
- Table 167. Market Growth Drivers and Trends in biofuels. 295
- Table 168. Biofuels Regulations. 295
- Table 169. Value chain: Biofuels. 297
- Table 170. Technology Readiness Level (TRL): Biofuels. 299
- Table 171. Addressable market size, billions USD 300
- Table 172. Risks and Opportunities in biofuels 301
- Table 173. Global revenues for biofuels, by type (2020-2037), billions USD. 301
- Table 174. Global Revenues for Biofuels, by Applications Market (2020-2037), billions USD. 302
- Table 175. Global revenues for biofuels, by regional market (2020-2037), billions USD. 302
- Table 176. Biofuels Company Profiles. 302
- Table 177. Types of bioplastics: 352
- Table 178. Polylactic acid (PLA) market analysis-manufacture, advantages, disadvantages and applications. 353
- Table 179. Types of PHAs and properties. 357
- Table 180. Commercially available PHAs. 358
- Table 181. Markets and applications for PHAs. 358
- Table 182. Bio-based Polyethylene (Bio-PE) market analysis- manufacture, advantages, disadvantages and 361
- Table 183. Bio-based Polyethylene terephthalate (Bio-PET) market analysis- manufacture, advantages, 361
- Table 184. Bio-based Polyethylene terephthalate (PET) producers and production capacities, 362
- Table 185. Key players in Bioplastics. 365
- Table 186. Market Growth Drivers and Trends in Bioplastics. 366
- Table 187. Bioplastics Regulations. 367
- Table 188. Value chain: Bioplastics. 367
- Table 189. Technology Readiness Level (TRL): Bioplastics. 369
- Table 190. Addressable market size for Bioplastics. 371
- Table 191. Risks and Opportunities in Bioplastics. 371
- Table 192. Global revenues for bioplastics, by type (2020-2037), billions USD. 372
- Table 193. Global revenues for bioplastics, by applications market (2020-2037), billions USD. 372
- Table 194. Global revenues for bioplastics, by regional market (2020-2037), billions USD. 373
- Table 195. Bioplastics Company Profiles. 373
- Table 196. Types of biochemicals. 517
- Table 197. Plant-based feedstocks and biochemicals produced. 519
- Table 198. Waste-based feedstocks and biochemicals produced. 520
- Table 199. Microbial and mineral-based feedstocks and biochemicals produced. 521
- Table 200. Biobased feedstock sources for Succinic acid. 523
- Table 201. Applications of succinic acid. 523
- Table 202. Biobased feedstock sources for itaconic acid. 524
- Table 203. Applications of bio-based itaconic acid. 524
- Table 204. Feedstock Sources for Citric Acid Production. 525
- Table 205. Applications of Citric Acid. 525
- Table 206. Feedstock Sources for Acetic Acid Production. 525
- Table 207. Applications of Acetic Acid. 525
- Table 208. Feedstock Sources for Acetic Acid Production. 526
- Table 209. Applications of Acetic Acid. 526
- Table 210. Common lysine sources that can be used as feedstocks for producing biochemicals. 527
- Table 211. Applications of lysine as a feedstock for biochemicals. 527
- Table 212. Feedstock Sources for Threonine Production. 528
- Table 213. Applications of Threonine. 528
- Table 214. Feedstock Sources for Methionine Production. 529
- Table 215. Applications of Methionine. 529
- Table 216. Vitamins Produced Using Biotechnology. 529
- Table 217. Biobased feedstock sources for ethanol. 534
- Table 218. Applications of bio-based ethanol. 534
- Table 219. Feedstock Sources for Butanol Production. 535
- Table 220. Applications of Butanol. 535
- Table 221. Biobased feedstock sources for isobutanol. 535
- Table 222. Applications of bio-based isobutanol. 536
- Table 223. Applications of bio-based 1,3-Propanediol (1,3-PDO). 536
- Table 224. Types of Biosurfactants. 537
- Table 225. Feedstock Sources for Biosurfactant Production 537
- Table 226. Applications of Biosurfactants 537
- Table 227. Rhamnolipid Production and Application Characteristics. 538
- Table 228. Sophorolipid Types and Application Properties. 539
- Table 229. Mannosylerythritol Lipid Variants and Properties. 540
- Table 230. Cellobiose Lipid Development and Applications. 541
- Table 231. Designer Biosurfactant Engineering Strategies 542
- Table 232. Feedstock Sources for APG Production 543
- Table 233. Applications of Alkyl Polyglucosides (APGs) 543
- Table 234. Feedstock Sources for Ethyl Lactate Production. 544
- Table 235. Applications of Ethyl Lactate. 544
- Table 236. Feedstock Sources for Dimethyl Carbonate Production 544
- Table 237. Applications of Dimethyl Carbonate 544
- Table 238. Markets and applications for bio-based glycerol. 545
- Table 239. Bio-manufactured Fragrances and Aromatics. 549
- Table 240. Biotech-derived Fragrance Precursors. 550
- Table 241. Bio-manufactured Enhancers. 552
- Table 242. Feedstock Sources for Succinic Acid Production 555
- Table 243. Applications of Succinic Acid. 555
- Table 244. Applications of bio-based 1,4-Butanediol (BDO). 555
- Table 245. Feedstock Sources for Isoprene Production. 556
- Table 246. Applications of Isoprene. 556
- Table 247. Applications of bio-based ethylene. 557
- Table 248. Applications of bio-based propylene. 557
- Table 249. Applications of bio-based adipic acid. 558
- Table 250. Applications of bio-based acrylic acid. 559
- Table 251. Bio-PBS market analysis-manufacture, advantages, disadvantages and applications. 562
- Table 252. Leading PBS producers and production capacities. 562
- Table 253. Polyethylene furanoate (PEF) market analysis-manufacture, advantages, disadvantages and applications. 563
- Table 254. FDCA and PEF producers. 564
- Table 255. Polytrimethylene terephthalate (PTT) market analysis-manufacture, advantages, disadvantages and 565
- Table 256. Production capacities of Polytrimethylene terephthalate (PTT), by leading producers. 565
- Table 257. Types of Wood-Plastic Composites (WPCs). 567
- Table 258. Types of Biofiber-Reinforced Plastics. 569
- Table 259. Types of Polymer Blends with Bio-based Components. 570
- Table 260. Hyaluronic Acid Production Parameters and Applications 572
- Table 261. Squalene/Squalane Production Methods and Characteristics. 573
- Table 262. Collagen Production Systems and Applications. 574
- Table 263. Bio-based UV Filter Compounds and Characteristics. 575
- Table 264. Melanin Production and Application Parameters. 576
- Table 265. Bio-manufactured Emollient Categories and Properties. 577
- Table 266. Mineral source products and applications. 583
- Table 267. Cement Alternatives from Biomanufacturing. 584
- Table 268. Precision Fermentation Products. 585
- Table 269. Key players in Biochemicals. 586
- Table 270. Bio-manufactured Beauty Ingredient Production Capacities 589
- Table 271. Market Growth Drivers and Trends in Biochemicals. 589
- Table 272. Trends and Drivers in Biotechnology. 590
- Table 273. Government Support of Biotechnology. 591
- Table 274. Biochemicals Regulations. 592
- Table 275. Value chain: Biochemicals. 593
- Table 276. Economic Viability Assessment Framework. 594
- Table 277. Feedstock Price Impact Analysis for Biotechnology Production. 595
- Table 278. Scale-up Cost Impact Analysis. 596
- Table 279. Addressable market size for Biochemicals. 598
- Table 280. Risks and Opportunities in Biochemicals. 599
- Table 281. Market Challenge Assessment and Mitigation Strategies. 600
- Table 282. Technical Challenge Assessment and Solutions. 601
- Table 283. Global revenues for biochemicals, by type (2020-2037), billions USD. 601
- Table 284. Global revenues for biochemicals, by applications market (2020-2037), billions USD. 602
- Table 285. Global revenues for biochemicals, by regional market (2020-2037), billions USD. 602
- Table 286. Biochemicals Company Profiles. 603
- Table 287. Bio-agritech categories. 622
- Table 288. Biopesticides: Pros and Cons. 623
- Table 289. Semiochemicals: Advantages and Disadvantages. 624
- Table 290. Biological Pest Control: Advantages and Disadvantages. 625
- Table 291. Global regulations on biopesticides. 625
- Table 292. Main types of microbial pesticides. 627
- Table 293. Main types of biochemical pesticides. 628
- Table 294. Main types of biofertilizers. 629
- Table 295. Types of Microbial Biostimulants. 635
- Table 296. Main types of non-microbial biostimulants. 639
- Table 297. Types of Agricultural Enzymes 640
- Table 298. Key players in Bio Agritech. 642
- Table 299. Market Growth Drivers and Trends in Bio Agritech 642
- Table 300. Bio Agritech Regulations. 643
- Table 301. Value chain: Bio Agritech. 643
- Table 302. Addressable market size for Bio Agritech. 645
- Table 303. Risks and Opportunities in Bio Agritech. 645
- Table 304. Global revenues for Bio Agritech products, by applications market (2020-2037), billions USD. 646
- Table 305. Global revenues for Bio Agritech products, by regional market (2020-2037), billions USD. 647
- Table 306. Bio agritech Company Profiles. 647
List of Figures
- Figure 1. CRISPR/Cas9 & Targeted Genome Editing. 119
- Figure 2. Genetic Circuit-Assisted Smart Microbial Engineering. 122
- Figure 3. Cell-free and cell-based protein synthesis systems. 124
- Figure 4. Microbial Chassis Development for Natural Product Biosynthesis. 125
- Figure 5. The design-make-test-learn loop of generative biology. 129
- Figure 6. Flow chart for biodiesel production. 236
- Figure 7. Biogas and biomethane pathways. 246
- Figure 8. Overview of biogas utilization. 248
- Figure 9. Biogas and biomethane pathways. 250
- Figure 10. Schematic overview of anaerobic digestion process for biomethane production. 251
- Figure 11. Schematic overview of biomass gasification for biomethane production. 252
- Figure 12. Properties of petrol and biobutanol. 257
- Figure 13. Biobutanol production route. 257
- Figure 14. Renewable Methanol Production Processes from Different Feedstocks. 267
- Figure 15. Production of biomethane through anaerobic digestion and upgrading. 268
- Figure 16. Production of biomethane through biomass gasification and methanation. 269
- Figure 17. Production of biomethane through the Power to methane process. 269
- Figure 18. Bio-oil upgrading/fractionation techniques. 275
- Figure 19. SWOT analysis for Bio-aviation fuel. 283
- Figure 20. Pathways for algal biomass conversion to biofuels. 287
- Figure 21. SWOT analysis for algae-derived biofuels. 288
- Figure 22. Algal biomass conversion process for biofuel production. 289
- Figure 23. PHA family. 357
- Figure 24. Schematic of biorefinery processes. 522
- Figure 25. Production capacities of Polyethylene furanoate (PEF) to 2025. 564
- Figure 26. Technology Readiness Level (TRL): Biochemicals. 598
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