The Global Industrial Biomanufacturing Market 2027-2037

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  • Published: August 2026
  • Pages: 689
  • Tables: 306
  • Figures: 26

 

Industrial biomanufacturing uses living systems — microbes, mammalian, plant and insect cells, and increasingly cell-free enzymatic platforms — to produce molecules that would otherwise be made from petrochemical feedstocks or extracted from natural sources. It spans six commercial domains: biopharmaceuticals, industrial enzymes, biofuels, bioplastics, biochemicals and bio-agritech. The sector's economic case rests on three arguments rather than one. The first is decarbonisation: biological routes displace fossil feedstocks across chemicals, fuels, materials and food ingredients, and where carbon pricing tightens the cost gap narrows structurally rather than cyclically. The second is supply-chain resilience, since fermentation can be sited close to demand and run on local or waste-derived carbon. This has become explicit policy: the United States enacted the BIOSECURE Act in December 2025 and its National Security Commission on Emerging Biotechnology has identified limited domestic scale-up capacity as a structural weakness, while China has published target product lists to direct investment. The third is value capture — biomanufacturing creates new industrial ecosystems in strain design, bioprocess engineering and downstream separation rather than merely substituting inputs.

Biopharmaceuticals remain the largest value pool, with an addressable market approaching $1 trillion by 2030 across monoclonal antibodies, vaccines, recombinant proteins and the faster-growing cell, gene and RNA therapeutic segments. Industrial enzymes represent a mature multi-billion dollar market. Biofuels are the largest volume segment, and bioplastics, biochemicals and bio-agritech expanding from smaller bases. The technology frontier is moving on several fronts simultaneously: AI-driven protein and pathway design compressing design-build-test cycles; continuous and intensified fermentation displacing batch operation; cell-free systems removing the constraints of cell viability; and alternative feedstocks — C1 gases, lignocellulosics and captured CO₂ — reducing dependence on food crops.

The sector's record also warrants caution. Between 2019 and 2026 POET halted cellulosic production at Project Liberty, Clariant closed its Podari plant and exited biofuels, Fulcrum BioEnergy and Red Rock Biofuels entered bankruptcy without completing commercial production, both Enerkem sites failed, and Viridos filed for Chapter 11 after ExxonMobil ended a $350 million algae programme. No commercial biomass gasification-Fischer-Tropsch plant operates anywhere. Announced capacity consistently exceeds realised capacity, and forecasts should be read as contingent on a scale-up that has repeatedly proven harder than projected.

The Global Industrial Biomanufacturing Market 2027-2037 provides a comprehensive assessment of industrial biomanufacturing across its six commercial domains, combining technology analysis, market forecasts to 2037 and profiles of more than 1,000 companies. Industrial biomanufacturing has moved from a substitution play to a matter of industrial strategy, driven by decarbonisation targets, supply-chain security concerns and the emergence of AI-enabled biological design. This report examines what is genuinely commercial, what remains pre-commercial, and where announced capacity has failed to materialise. Coverage begins with production platforms — microbial fermentation, mammalian, plant and insect cell culture, transgenic systems and cell-free biomanufacturing — before addressing enabling technologies including synthetic biology, CRISPR-based strain engineering, continuous and intensified processing, downstream separation, and AI and robotics in bioprocess design.

Six market chapters then assess biopharmaceuticals, industrial enzymes, biofuels, bioplastics, biochemicals and bio-agritech. Each covers technology and materials analysis, market drivers, regulations, value chain, technology readiness, addressable market size, risks and opportunities, and global revenue forecasts segmented by product type, application and region. The report includes revenue and volume forecasts to 2037, capacity and consumption series for renewable diesel, biodiesel, bio-jet fuel, bioethanol, biomethane and bio-LNG, and detailed assessments of feedstock availability including waste lipids, lignocellulosics, C1 and C2 gases, and captured CO₂. More than 1,080 companies are profiled with descriptions, country of operation and website. 

Contents

  • Executive Summary — definition and scope, processes, key components, economic importance, colours of biotechnology, markets, AI and robotics, emerging technologies
  • Production — microbial fermentation, mammalian cell culture, plant cell culture, insect cell culture, transgenic animals and plants, technologies, scale, mode of operation, host organisms
  • Biopharmaceuticals — overview, technology analysis, market analysis, company profiles
  • Industrial Enzymes (Biocatalysts) — overview, technology analysis, market analysis, company profiles
  • Biofuels — overview, technology analysis, market analysis, company profiles
  • Bioplastics — overview, technology analysis, market analysis, company profiles
  • Biochemicals — overview, technology analysis, market analysis, company profiles
  • Bio-Agritech — overview, technology analysis, market analysis, company profiles

 

Companies profiled include 3Bar Biologics, 3DBioFibR, 3M, 9Fiber, Inc., AbbVie, Absci Corp, Adaptive Symbiotic Technologies, ADBioplastics, Adjuvants Plus, Adriano di Marti/Desserto, Aduro Clean Technologies, Inc., Advanced Biochemical (Thailand) Co., Ltd., Aemetis, Inc., AEP Polymers, Aeropowder Limited, AFINGEN®, Afyren, AGAE Technologies LLC, Again Bio, AgBiome, Agilyx, Agra Energy, Agragene, AGRANA Staerke GmbH, Agrinos, Agrivida, Agrobiomics, AgroRenew, AgroSpheres, Ahlstrom-Munksjö Oyj, AI Proteins, Air Company, Aircela Inc, Alexion Pharmaceuticals, Algaeing, Algal Bio Co., Ltd., Algenesis Corporation, Algenie, Algenl, Algenol, Alginor ASA, Algix LLC, Allied Carbon Solutions, Allozymes, Alnylam Pharmaceuticals, Alpha Biofuels (Singapore) Pte Ltd, Alto Neuroscience, AM Green, Amano Enzyme Inc., Amatera, Amfora, Amgen, AmicaTerra, Aminoverse, Amphista Therapeutics, AmphiStar, Amply Discovery, AMSilk GmbH, An Phát Bioplastics, Ananas Anam Ltd., Andermatt Biocontrol, Andritz AG, Anellotech, Inc., Ankor Bioplastics Co., Ltd., Anodyne Chemistries, ANPOLY, Inc., Anqing He Xing Chemical Co., Ltd., Ansa Biotechnologies, Antheia, APChemi Pvt. Ltd., Apeiron Bioenergy, Aperam BioEnergia, Apexzymes, Aphea.Bio, Applied Bioplastics, Applied Research Associates, Inc. (ARA), Aqemia, Aquafil S.p.A., Aquapak Polymers Ltd, Arcadia Biosciences, Arcadia eFuels, Archer Daniel Midland Company (ADM), Arctic Biomaterials Oy, Ardra Bio, Arekapak GmbH, Arkema S.A, Arlanxeo, Arrow Greentech, Arysta LifeScience, Arzeda, Arzeda Corp., Asahi Kasei Chemicals Corporation, ASB Biodiesel Limited, Ascribe Bioscience, AstraZeneca, Atantares, Athos Therapeutics, Atlántica Agrícola, Atmonia, Atomwise, Attis Innovations, llc, Aurigene Pharmaceutical Services, AVA Biochem AG, Avalon BioEnergy, Avani Eco, Avantium B.V., Avicenna Biosciences, Avient Corporation, Avioxx, Axcelon Biopolymers Corporation, Ayas Renewables Inc., Azolla, Azotic Technologies, B-PREG, Balrampur Chini Mills, Bambooder Biobased Fibers B.V., Basecamp Research, BASF, BASF SE, Bast Fiber Technologies, Inc., Bayer CropScience, BBCA Biochemical & GALACTIC Lactic Acid Co., Ltd., Bcomp ltd., BDI-BioEnergy International GmbH, BEE Biofuel, Bee Vectoring Technologies, BeiGene, Benefuel Inc., BenevolentAI, Better Fibre Technologies, Betulium Oy, Beyond Leather Materials ApS, BigHat Biosciences, BigSis, Bio Fab NZ, BIO-FED, BIO-LUTIONS International AG, Bio-Oils, Bio2Materials Sp. z o.o., Bio2Oil ApS, BioAge Labs, Biobest, BioBetter, Biocatalysts Ltd., Bioceres Crop Solutions, Biocon, BioConsortia, BIOD Energy, BioEnz Technologies, Bioextrax AB, Biofiber Tech Sweden AB, Biofibre GmbH, Biofine Technology, LLC, Bioform Technologies, Biofy, BiogasClean A/S, Biogen, Biojet AS, Biokemik, Bioleather, Biolevel, Biolexis Therapeutics, Bioline AgroSciences, BIOLO, BioLogiQ, Inc., BioMap, Biomass Resin Holdings Co., Ltd., Biomatter, Biomatter Designs, Biome Bioplastics, Biome Makers, Bionema, BioNTech, BioPhero, Biophilica, BioPhy, Bioplastech Ltd, Bioplastix, Biopolax, Bioptimus SAS, BioSolutions, Biosyntia, Biotalys, BIOTEC GmbH & Co. KG, Biotecam, Biotechnology SL, Biotelliga, Biotensidion GmbH, Biotic Circular Technologies Ltd., Biotrem, Biotrop, Biovox, Bioweg, bitBiome, BlockTexx Pty Ltd., Bloom Biorenewables SA, BluCon Biotech GmbH, Blue BioFuels, Inc., Blue Ocean Closures, BlueAlp Technology, Bluepha Beijing Lanjing Microbiology Technology Co., Ltd., Bolt Threads, Bontera, Boreal Bioproducts, Borealis AG, Borregaard Chemcell, Bosk Bioproducts Inc., Botanical Solutions, Bowil Biotech Sp. z o.o., Braskem SA, Braven Environmental, LLC, Brightmark Energy, Brightseed, Bristol Myers Squibb, bse Methanol GmbH, BTG Bioliquids B.V., Bucha Bio, Inc., Burgo Group S.p.A., Buyo Bioplastic Ltd., Byogy Renewables, Inc., B’ZEOS, C-Zero Inc., C1 Green Chemicals AG, C16 Biosciences, Cambrium GmbH, Caphenia GmbH, CARAPAC Company, Carapace Biopolymers, Carbiolice, Carbios, Carbon Collect Limited, Carbon Crusher, Carbon Engineering Ltd., Carbon Infinity Limited, Carbon Recycling International, Carbon Sink LLC, Carbonade, CarbonBridge, Carbonwave, Carbyon BV, Cardia Bioplastics Ltd., Cardolite, Cargill, Cascade Biocatalysts, Cascade Biocatalysts, Inc., Cass Materials Pty Ltd, Cassandra Oil AB, Casterra Ag Ltd., Catalyxx, Cathay Industrial Biotech, Ltd., Celanese Corporation, Cellicon B.V., CellON, Celltrion, Cellucomp Ltd., Celluforce, Cellugy, Cellutech AB (Stora Enso), Celtic Renewables Ltd., Century Health Technology, Inc., Ceradis, Cereal Process Technologies (CPT), CERT Systems, Inc., Certis USA, CF Industries Holdings, Inc., CH-Bioforce Oy, ChainCraft, ChakraTech, Checkerspot, Inc., Chempolis Oy, Chestnut Bio Polymers, ChiralVision B.V., Chitelix, Chitose Bio Evolution Pte Ltd., Chongqing Bofei Biochemical Products Co., Ltd., Chuetsu Pulp & Paper Co., Ltd., Cibus, CIMV, CinderBio, Circa Group, Circla Nordic, Circular Systems, CJ Biomaterials, Inc., Clariant, Clariant AG, CleanJoule, Climeworks, CNF Biofuel AS, CO2BioClean, Coastgrass ApS, Codexis, COFCO Cooperation Ltd., Coffeeco Upcycle, Conagen, Concentric Agriculture, Concord Blue Engineering, Constructive Bio, Cool Planet Energy Systems, Corn Next, Corsair Group International, Corteva Agriscience, Corumat, Inc. and more....

 

 

 

 

 

 

 

 

1             EXECUTIVE SUMMARY            28

  • 1.1        Definition and Scope of Industrial Biomanufacturing        28
  • 1.2        Overview of Industrial Biomanufacturing Processes           29
  • 1.3        Key Components of Industrial Biomanufacturing 31
  • 1.4        Importance of Industrial Biomanufacturing in the Global Economy          32
  • 1.5        Colours of Biotechnology      32
  • 1.6        Markets              33
    • 1.6.1    Biopharmaceuticals 33
    • 1.6.2    Industrial Enzymes    34
    • 1.6.3    Biofuels             34
    • 1.6.4    Biomaterials and Bioplastics              35
    • 1.6.5    Specialty Chemicals 36
    • 1.6.6    Food and Beverage    36
    • 1.6.7    Agriculture and Animal Health           37
    • 1.6.8    Environmental Biotechnology             38
  • 1.7        AI and Robotics in Biomanufacturing            39
  • 1.8        Other Advanced and Emerging Technologies in Biomanufacturing           40

 

2             PRODUCTION               42

  • 2.1        Microbial Fermentation           42
  • 2.2        Mammalian Cell Culture        42
  • 2.3        Plant Cell Culture        43
  • 2.4        Insect Cell Culture     43
    • 2.4.1    Overview           43
    • 2.4.2    Cell lines           44
    • 2.4.3    Process characteristics          44
    • 2.4.4    Glycosylation 44
    • 2.4.5    Commercial applications      44
    • 2.4.6    Position within industrial biomanufacturing             45
  • 2.5        Transgenic Animals   45
  • 2.6        Transgenic Plants        46
  • 2.7        Technologies  46
    • 2.7.1    Upstream Processing               46
      • 2.7.1.1 Cell Culture     46
        • 2.7.1.1.1           Overview           46
        • 2.7.1.1.2           Types of Cell Culture Systems            46
        • 2.7.1.1.3           Factors Affecting Cell Culture Performance              47
        • 2.7.1.1.4           Advances in Cell Culture Technology             48
          • 2.7.1.1.4.1      Single-use systems   48
          • 2.7.1.1.4.2      Process analytical technology (PAT)               48
          • 2.7.1.1.4.3      Cell line development              48
    • 2.7.2    Fermentation 49
      • 2.7.2.1 Overview           49
        • 2.7.2.1.1           Types of Fermentation Processes    49
        • 2.7.2.1.2           Factors Affecting Fermentation Performance          49
        • 2.7.2.1.3           Advances in Fermentation Technology         50
          • 2.7.2.1.3.1      High-cell-density fermentation          50
          • 2.7.2.1.3.2      Continuous processing           50
          • 2.7.2.1.3.3      Metabolic engineering             51
          • 2.7.2.1.3.4      Synthetic biology applications           51
          • 2.7.2.1.3.5      Cell-free systems        51
          • 2.7.2.1.3.6      Continuous vs batch biomanufacturing      52
    • 2.7.3    Downstream Processing        53
      • 2.7.3.1 Purification      53
        • 2.7.3.1.1           Overview           53
        • 2.7.3.1.2           Types of Purification Methods            53
        • 2.7.3.1.3           Factors Affecting Purification Performance               53
        • 2.7.3.1.4           Advances in Purification Technology              54
          • 2.7.3.1.4.1      Affinity chromatography         54
          • 2.7.3.1.4.2      Membrane chromatography 54
          • 2.7.3.1.4.3      Continuous chromatography              55
          • 2.7.3.1.4.4      Downstream processing (DSP) improvements        55
          • 2.7.3.1.4.5      Tangential flow filtration (TFF) in downstream bioprocessing        56
    • 2.7.4    Formulation    57
      • 2.7.4.1 Overview           57
        • 2.7.4.1.1           Types of Formulation Methods           57
        • 2.7.4.1.2           Factors Affecting Formulation Performance             57
        • 2.7.4.1.3           Advances in Formulation Technology            58
          • 2.7.4.1.3.1      Controlled release      58
          • 2.7.4.1.3.2      Nanoparticle formulation      58
          • 2.7.4.1.3.3      3D printing       58
    • 2.7.5    Bioprocess Development      58
      • 2.7.5.1 Scale-up            58
        • 2.7.5.1.1           Overview           58
        • 2.7.5.1.2           Factors Affecting Scale-up Performance     59
        • 2.7.5.1.3           Scale-up Strategies    60
      • 2.7.5.2 Optimization  60
        • 2.7.5.2.1           Overview           60
        • 2.7.5.2.2           Factors Affecting Optimization Performance            60
        • 2.7.5.2.3           Optimization Strategies           61
        • 2.7.5.2.4           Machine learning to improve biomanufacturing processes            62
        • 2.7.5.2.5           Process intensification and high-cell-density fermentation           64
        • 2.7.5.2.6           Hybrid biotechnological-chemical approaches     66
    • 2.7.6    Analytical Methods    68
      • 2.7.6.1 Quality Control             68
        • 2.7.6.1.1           Overview           68
        • 2.7.6.1.2           Types of Quality Control Tests            68
        • 2.7.6.1.3           Factors Affecting Quality Control Performance      70
      • 2.7.6.2 Characterization          70
        • 2.7.6.2.1           Overview           70
        • 2.7.6.2.2           Types of Characterization Methods 71
        • 2.7.6.2.3           Factors Affecting Characterization Performance   72
    • 2.7.7    Synthetic Biology Tools and Techniques      73
      • 2.7.7.1 DNA synthesis              73
      • 2.7.7.2 CRISPR-Cas9 systems            74
      • 2.7.7.3 Protein/enzyme engineering 74
      • 2.7.7.4 Computer-aided design          75
      • 2.7.7.5 Strain construction and optimization            76
      • 2.7.7.6 Robotics and automation      77
      • 2.7.7.7 Artificial intelligence and machine learning              78
    • 2.7.8    Alternative Feedstocks and Sustainability 79
      • 2.7.8.1 C1 feedstocks: Metabolic pathways               79
      • 2.7.8.2 C2 feedstocks               80
      • 2.7.8.3 Lignocellulosic biomass feedstocks              81
      • 2.7.8.4 Blue biotechnology feedstocks         82
      • 2.7.8.5 Routes for carbon capture in biotechnology             83
  • 2.8        Scale of Production   84
    • 2.8.1    Laboratory Scale         84
      • 2.8.1.1 Overview           84
      • 2.8.1.2 Scale and Equipment               84
      • 2.8.1.3 Advantages     85
      • 2.8.1.4 Disadvantages             85
    • 2.8.2    Pilot Scale        86
      • 2.8.2.1 Overview           86
      • 2.8.2.2 Scale and Equipment               86
      • 2.8.2.3 Advantages     86
      • 2.8.2.4 Disadvantages             87
    • 2.8.3    Commercial Scale      87
      • 2.8.3.1 Overview           87
      • 2.8.3.2 Scale and Equipment               87
      • 2.8.3.3 Advantages     88
      • 2.8.3.4 Disadvantages             89
  • 2.9        Mode of Operation     89
    • 2.9.1    Batch Production        89
      • 2.9.1.1 Overview           89
      • 2.9.1.2 Advantages     90
      • 2.9.1.3 Disadvantages             90
      • 2.9.1.4 Applications   91
    • 2.9.2    Fed-batch Production              91
      • 2.9.2.1 Overview           91
      • 2.9.2.2 Advantages     91
      • 2.9.2.3 Disadvantages             92
      • 2.9.2.4 Applications   92
    • 2.9.3    Continuous Production           92
      • 2.9.3.1 Overview           92
      • 2.9.3.2 Advantages     92
      • 2.9.3.3 Disadvantages             93
      • 2.9.3.4 Applications   93
      • 2.9.3.5 Key fermentation parameter comparison   93
    • 2.9.4    Cell factories for biomanufacturing 95
      • 2.9.4.1 Range of organisms  96
      • 2.9.4.2 Escherichia coli (E.coli)           97
      • 2.9.4.3 Corynebacterium glutamicum (C. glutamicum)     98
      • 2.9.4.4 Bacillus subtilis (B. subtilis) 99
      • 2.9.4.5 Saccharomyces cerevisiae (S. cerevisiae)  100
      • 2.9.4.6 Yarrowia lipolytica (Y. lipolytica)        101
      • 2.9.4.7 Non-model organisms            101
    • 2.9.5    Perfusion Culture        103
      • 2.9.5.1 Overview           103
      • 2.9.5.2 Advantages     103
      • 2.9.5.3 Disadvantages             103
      • 2.9.5.4 Applications   103
      • 2.9.5.5 Perfusion bioreactors               104
    • 2.9.6    Other Modes of Operation     105
      • 2.9.6.1 Immobilized Cell Culture       105
        • 2.9.6.1.1           Immobilized enzymes              105
        • 2.9.6.1.2           Immobilized catalysts              106
      • 2.9.6.2 Two-Stage Production              107
      • 2.9.6.3 Hybrid Systems            107
  • 2.10     Host Organisms          108

 

3             BIOPHARMACEUTICALS        110

  • 3.1        Overview           110
  • 3.2        Technology/materials analysis          110
    • 3.2.1    Monoclonal Antibodies (mAbs)         110
    • 3.2.2    Recombinant Proteins             111
    • 3.2.3    Vaccines           111
    • 3.2.4    Cell and Gene Therapies        112
    • 3.2.5    Blood Factors 113
    • 3.2.6    Tissue Engineering Products                113
    • 3.2.7    Nucleic Acid Therapeutics    114
    • 3.2.8    Peptide Therapeutics               114
    • 3.2.9    Biosimilars and Biobetters    115
    • 3.2.10 Nanobodies and Antibody Fragments           116
    • 3.2.11 Synthetic biology         116
      • 3.2.11.1            Metabolic engineering             117
        • 3.2.11.1.1        DNA synthesis              117
        • 3.2.11.1.2        CRISPR              118
          • 3.2.11.1.2.1   CRISPR/Cas9-modified biosynthetic pathways      118
      • 3.2.11.2            Protein/Enzyme Engineering                119
      • 3.2.11.3            Strain construction and optimization            120
      • 3.2.11.4            Synthetic biology and metabolic engineering           121
      • 3.2.11.5            Smart bioprocessing 121
      • 3.2.11.6            Cell-free systems        122
      • 3.2.11.7            Chassis organisms    124
      • 3.2.11.8            Biomimetics   125
      • 3.2.11.9            Sustainable materials              126
      • 3.2.11.10         Robotics and automation      126
        • 3.2.11.10.1     Robotic cloud laboratories   127
        • 3.2.11.10.2     Automating organism design              127
        • 3.2.11.10.3     Artificial intelligence and machine learning              127
      • 3.2.11.11         Fermentation Processes        128
    • 3.2.12 Generative Biology     128
      • 3.2.12.1            Generative Adversarial Networks (GANs)    130
        • 3.2.12.1.1        Variational Autoencoders (VAEs)      130
        • 3.2.12.1.2        Normalizing Flows      130
        • 3.2.12.1.3        Autoregressive Models            130
        • 3.2.12.1.4        Evolutionary Generative Models       131
      • 3.2.12.2            Design Optimization 131
        • 3.2.12.2.1        Evolutionary Algorithms (e.g., Genetic Algorithms, Evolutionary Strategies)       131
          • 3.2.12.2.1.1   Genetic Algorithms (GAs)      131
          • 3.2.12.2.1.2   Evolutionary Strategies (ES) 131
        • 3.2.12.2.2        Reinforcement Learning         132
        • 3.2.12.2.3        Multi-Objective Optimization              132
        • 3.2.12.2.4        Bayesian Optimization            132
      • 3.2.12.3            Computational Biology           133
        • 3.2.12.3.1        Molecular Dynamics Simulations    133
        • 3.2.12.3.2        Quantum Mechanical Calculations                134
        • 3.2.12.3.3        Systems Biology Modeling    134
        • 3.2.12.3.4        Metabolic Engineering Modeling       135
      • 3.2.12.4            Data-Driven Approaches       135
        • 3.2.12.4.1        Machine Learning       136
        • 3.2.12.4.2        Graph Neural Networks           136
        • 3.2.12.4.3        Unsupervised Learning           136
        • 3.2.12.4.4        Active Learning and Bayesian Optimization              137
      • 3.2.12.5            Agent-Based Modeling            137
      • 3.2.12.6            Hybrid Approaches    138
  • 3.3        Market analysis            139
    • 3.3.1    Key players and competitive landscape      139
    • 3.3.2    Market Growth Drivers and Trends   140
    • 3.3.3    Regulations     141
    • 3.3.4    Value chain     142
    • 3.3.5    Future outlook              143
    • 3.3.6    Technology Readiness Level (TRL)   143
    • 3.3.7    Addressable Market Size        145
    • 3.3.8    Risks and Opportunities         145
    • 3.3.9    Global revenues           147
      • 3.3.9.1 By application market              147
      • 3.3.9.2 By regional market      148
    • 3.4        Company profiles       148

 

4             INDUSTRIAL ENZYMES (BIOCATALYSTS)      170

  • 4.1        Overview           170
    • 4.1.1    Bio-manufactured enzymes 170
  • 4.2        Technology/materials analysis          171
    • 4.2.1    Detergent Enzymes    171
    • 4.2.2    Food Processing Enzymes    172
    • 4.2.3    Textile Processing Enzymes  172
    • 4.2.4    Paper and Pulp Processing Enzymes             173
    • 4.2.5    Leather Processing Enzymes               173
    • 4.2.6    Biofuel Production Enzymes                174
      • 4.2.6.1 Enzymes for lignocellulosic derived bioethanol      174
      • 4.2.6.2 Cellulases for lignocellulosic bioethanol    175
      • 4.2.6.3 Hemicellulases and synergistic enzyme cocktails                176
      • 4.2.6.4 Thermostable and extremophilic enzymes 177
      • 4.2.6.5 Cost-performance metrics for thermostable enzymes      178
    • 4.2.7    Animal Feed Enzymes              179
    • 4.2.8    Pharmaceutical and Diagnostic Enzymes  180
    • 4.2.9    Waste Management and Bioremediation Enzymes              180
      • 4.2.9.1 Enzymes for plastics recycling           181
      • 4.2.9.2 Enzymatic depolymerization               182
      • 4.2.9.3 Challenges in enzymatic depolymerization               183
    • 4.2.10 Agriculture and Crop Improvement Enzymes           183
    • 4.2.11 Enzymes for Decarbonization and CO₂ Utilization 185
      • 4.2.11.1            Carbonic anhydrase in CO₂ capture technologies 187
      • 4.2.11.2            Formate dehydrogenase and CO₂-to-chemicals pathways             188
      • 4.2.11.3            Selected enzymatic approaches to CO2 capture and conversion              189
  • 4.3        Market analysis            190
    • 4.3.1    Key players and competitive landscape      190
    • 4.3.2    Market Growth Drivers and Trends   191
    • 4.3.3    Technology challenges and opportunities for industrial enzymes               192
    • 4.3.4    Economic competitiveness of enzymatic processing         194
    • 4.3.5    Regulations     194
    • 4.3.6    Value chain     195
    • 4.3.7    Future outlook              196
    • 4.3.8    Technology Readiness Level (TRL)   197
    • 4.3.9    Addressable Market Size        197
    • 4.3.10 Risks and Opportunities         198
    • 4.3.11 Global revenues           199
      • 4.3.11.1            By application market              199
      • 4.3.11.2            By regional market      199
  • 4.4        Company profiles       200

 

5             BIOFUELS        213

  • 5.1        Overview           213
  • 5.2        Technology/materials analysis          215
    • 5.2.1    Role in the circular economy               215
    • 5.2.2    The global biofuels market    217
    • 5.2.3    Feedstocks      217
      • 5.2.3.1 First-generation (1-G)               218
      • 5.2.3.2 Second-generation (2-G)       219
        • 5.2.3.2.1           Lignocellulosic wastes and residues             220
        • 5.2.3.2.2           Biorefinery lignin         222
      • 5.2.3.3 Third-generation (3-G)             226
        • 5.2.3.3.1           Algal biofuels 226
          • 5.2.3.3.1.1      Properties         227
          • 5.2.3.3.1.2      Advantages     227
      • 5.2.3.4 Fourth-generation (4-G)          228
      • 5.2.3.5 Advantages and disadvantages, by generation        229
    • 5.2.4    Bioethanol       230
      • 5.2.4.1 First-generation bioethanol (from sugars and starches)    230
      • 5.2.4.2 Second-generation bioethanol (from lignocellulosic biomass)   230
      • 5.2.4.3 Third-generation bioethanol (from algae)    231
    • 5.2.5    Biodiesel           231
      • 5.2.5.1 Biodiesel by generation           231
      • 5.2.5.2 Production of biodiesel and other biofuels 232
        • 5.2.5.2.1           Pyrolysis of biomass 233
        • 5.2.5.2.2           Vegetable oil transesterification       236
        • 5.2.5.2.3           Vegetable oil hydrogenation (HVO)  237
          • 5.2.5.2.3.1      Production process   237
        • 5.2.5.2.4           Biodiesel from tall oil                239
        • 5.2.5.2.5           Fischer-Tropsch BioDiesel     239
        • 5.2.5.2.6           Hydrothermal liquefaction of biomass         242
        • 5.2.5.2.7           CO2 capture and Fischer-Tropsch (FT)          242
        • 5.2.5.2.8           Dymethyl ether (DME)              243
      • 5.2.5.3 Prices  243
      • 5.2.5.4 Global production and consumption            244
    • 5.2.6    Biogas 245
      • 5.2.6.1 Feedstocks      247
      • 5.2.6.2 Biomethane    248
        • 5.2.6.2.1           Production pathways                250
          • 5.2.6.2.1.1      Landfill gas recovery 250
          • 5.2.6.2.1.2      Anaerobic digestion  250
          • 5.2.6.2.1.3      Thermal gasification 251
      • 5.2.6.3 Global production      252
      • 5.2.6.4 Prices  252
        • 5.2.6.4.1           Raw Biogas     252
        • 5.2.6.4.2           Upgraded Biomethane            253
      • 5.2.6.5 Bio-LNG             253
        • 5.2.6.5.1           Markets              253
          • 5.2.6.5.1.1      Trucks 253
          • 5.2.6.5.1.2      Marine 253
        • 5.2.6.5.2           Plants 253
      • 5.2.6.6 bio-CNG (compressed natural gas derived from biogas)  254
      • 5.2.6.7 Carbon capture from biogas               254
      • 5.2.6.8 Biosyngas        255
        • 5.2.6.8.1           Production       255
        • 5.2.6.8.2           Prices  256
    • 5.2.7    Biobutanol      256
      • 5.2.7.1 Production       258
      • 5.2.7.2 Prices  258
    • 5.2.8    Biohydrogen   259
      • 5.2.8.1 Description     259
        • 5.2.8.1.1           Dark fermentation      259
        • 5.2.8.1.2           Photofermentation     260
        • 5.2.8.1.3           Biophotolysis (direct and indirect)   260
          • 5.2.8.1.3.1      Direct Biophotolysis: 260
          • 5.2.8.1.3.2      Indirect Biophotolysis:            261
      • 5.2.8.2 Production of biohydrogen from biomass  262
        • 5.2.8.2.1           Biological Conversion Routes             262
          • 5.2.8.2.1.1      Bio-photochemical Reaction              262
          • 5.2.8.2.1.2      Fermentation and Anaerobic Digestion        263
        • 5.2.8.2.2           Thermochemical conversion routes               263
          • 5.2.8.2.2.1      Biomass Gasification               263
          • 5.2.8.2.2.2      Biomass Pyrolysis      263
          • 5.2.8.2.2.3      Biomethane Reforming           264
      • 5.2.8.3 Applications   264
      • 5.2.8.4 Prices  265
    • 5.2.9    Biomethanol  265
      • 5.2.9.1 Gasification-based biomethanol     265
      • 5.2.9.2 Biosynthesis-based biomethanol    266
      • 5.2.9.3 Methanol-to gasoline technology     266
        • 5.2.9.3.1           Production processes              267
          • 5.2.9.3.1.1      Anaerobic digestion  268
          • 5.2.9.3.1.2      Biomass gasification 268
          • 5.2.9.3.1.3      Power to Methane       269
    • 5.2.10 Bio-oil and Biochar    269
      • 5.2.10.1            Pyrolysis-based bio-oil            270
      • 5.2.10.2            Hydrothermal liquefaction-based bio-oil    271
      • 5.2.10.3            Biochar from pyrolysis and gasification processes               271
      • 5.2.10.4            Advantages of bio-oils             273
      • 5.2.10.5            Production       274
        • 5.2.10.5.1        Fast Pyrolysis 274
        • 5.2.10.5.2        Costs of production  274
        • 5.2.10.5.3        Upgrading        274
      • 5.2.10.6            Applications   275
      • 5.2.10.7            Bio-oil producers         276
      • 5.2.10.8            Prices  276
        • 5.2.10.8.1        Biochar co-product economics         277
        • 5.2.10.8.2        Biochar in anaerobic digestion          278
    • 5.2.11 Renewable Diesel and Jet Fuel           278
      • 5.2.11.1            Renewable diesel        278
        • 5.2.11.1.1        Production       278
        • 5.2.11.1.2        Global consumption 279
        • 5.2.11.1.3        Prices  280
      • 5.2.11.2            Bio-aviation fuel (bio-jet fuel, sustainable aviation fuel, renewable jet fuel or aviation biofuel)              280
        • 5.2.11.2.1        Description     280
        • 5.2.11.2.2        SWOT analysis              282
        • 5.2.11.2.3        Global production and consumption            283
        • 5.2.11.2.4        Production pathways                283
        • 5.2.11.2.5        Prices  284
        • 5.2.11.2.6        Bio-aviation fuel production capacities       285
        • 5.2.11.2.7        Challenges      285
        • 5.2.11.2.8        Global consumption 286
    • 5.2.12 Algal biofuels 286
      • 5.2.12.1            Conversion pathways               286
      • 5.2.12.2            SWOT analysis              287
      • 5.2.12.3            Production       288
      • 5.2.12.4            Market challenges      289
      • 5.2.12.5            Prices  290
      • 5.2.12.6            Producers         291
  • 5.3        Market analysis            292
    • 5.3.1    Key players and competitive landscape      292
    • 5.3.2    Market Growth Drivers and Trends   295
    • 5.3.3    Regulations     295
    • 5.3.4    Value chain     296
    • 5.3.5    Future outlook              297
    • 5.3.6    Technology Readiness Level (TRL)   299
    • 5.3.7    Addressable Market Size        300
    • 5.3.8    Risks and Opportunities         301
    • 5.3.9    Global revenues           301
      • 5.3.9.1 By biofuel type               301
      • 5.3.9.2 Applications Market  302
      • 5.3.9.3 By regional market      302
  • 5.4        Company profiles       302

 

6             BIOPLASTICS 351

  • 6.1        Overview           352
  • 6.2        Technology/materials analysis          353
    • 6.2.1    Polylactic acid (PLA) 353
      • 6.2.1.1 NatureWorks: second global manufacturing site, Thailand            354
      • 6.2.1.2 PLA and PEF product developments (2026)              354
      • 6.2.1.3 Henan Techuang Biotechnology        354
    • 6.2.2    Polyhydroxyalkanoates (PHAs)          355
      • 6.2.2.1 Types   356
      • 6.2.2.2 Polyhydroxybutyrate (PHB)   359
      • 6.2.2.3 Polyhydroxyvalerate (PHV)    360
      • 6.2.2.4 Ourobio: PHAs and pigments from waste streams               360
      • 6.2.2.5 Shellworks: Vivomer PHA packaging             360
    • 6.2.3    Bio-based polyethylene (PE)                361
    • 6.2.4    Bio-based polyethylene terephthalate (PET)             361
    • 6.2.5    Bio-based polyurethanes (PUs)         362
    • 6.2.6    Starch-based plastics              363
    • 6.2.7    Cellulose-based plastics       364
      • 6.2.7.1 Ecovative Forager: mycelium hides and foams       364
  • 6.3        Market analysis            365
    • 6.3.1    Key players and competitive landscape      365
    • 6.3.2    Market Growth Drivers and Trends   366
      • 6.3.2.1 European biobased lead markets and demand-side measures   366
    • 6.3.3    Regulations     366
    • 6.3.4    Value chain     367
    • 6.3.5    Future outlook              368
      • 6.3.5.1 Effect of 2026 developments on the outlook            369
    • 6.3.6    Technology Readiness Level (TRL)   369
    • 6.3.7    Addressable Market Size        371
    • 6.3.8    Risks and Opportunities         371
    • 6.3.9    Global revenues           372
      • 6.3.9.1 By type                372
      • 6.3.9.2 By application market              372
      • 6.3.9.3 By regional market      373
  • 6.4        Company profiles       373

 

7             BIOCHEMICALS           517

  • 7.1        Overview           517
  • 7.2        Technology/materials analysis          519
    • 7.2.1    Organic acids 522
      • 7.2.1.1 Lactic acid       522
        • 7.2.1.1.1           D-lactic acid   522
        • 7.2.1.1.2           L-lactic acid    522
      • 7.2.1.2 Succinic acid 523
      • 7.2.1.3 Itaconic acid  524
      • 7.2.1.4 Citric acid        525
      • 7.2.1.5 Acetic acid      525
      • 7.2.1.6 Malonic acid   526
    • 7.2.2    Amino acids   526
      • 7.2.2.1 Glutamic acid                526
      • 7.2.2.2 Lysine 527
      • 7.2.2.3 Threonine         528
      • 7.2.2.4 Methionine      529
      • 7.2.2.5 Vitamins produced using biotechnology     529
        • 7.2.2.5.1           Vitamin B2 (Riboflavin)            530
        • 7.2.2.5.2           Vitamin B12 (Cobalamin)      530
        • 7.2.2.5.3           Vitamin C (Ascorbic Acid)      531
        • 7.2.2.5.4           Vitamin B7 (Biotin)     532
        • 7.2.2.5.5           Vitamin B3 (Niacin / Nicotinic Acid) 532
        • 7.2.2.5.6           Vitamin B9 (Folic Acid / Folate)          533
    • 7.2.3    Alcohols            534
      • 7.2.3.1 Ethanol              534
      • 7.2.3.2 Butanol              534
      • 7.2.3.3 Isobutanol       535
      • 7.2.3.4 Propanediol    536
      • 7.2.3.5 Catalyxx: commercial-scale renewable alcohols, Sines, Portugal             537
    • 7.2.4    Surfactants     537
      • 7.2.4.1 Biosurfactants (e.g., rhamnolipids, sophorolipids)              537
        • 7.2.4.1.1           Rhamnolipids 538
        • 7.2.4.1.2           Sophorolipids                539
        • 7.2.4.1.3           Mannosylerythritol lipids (MELs)      540
        • 7.2.4.1.4           Cellobiose lipids          541
        • 7.2.4.1.5           Designer glycolipids and lipopeptides via synthetic biology           542
      • 7.2.4.2 Alkyl polyglucosides (APGs) 543
    • 7.2.5    Solvents            543
      • 7.2.5.1 Ethyl lactate    543
      • 7.2.5.2 Dimethyl carbonate   544
      • 7.2.5.3 Glycerol             545
    • 7.2.6    Flavours and fragrances         545
      • 7.2.6.1 Vanillin               545
      • 7.2.6.2 Nootkatone     546
      • 7.2.6.3 Limonene         547
      • 7.2.6.4 Bio-manufactured fragrances and aromatics          548
      • 7.2.6.5 Biotech-derived fragrance precursors           549
      • 7.2.6.6 Ambroxan        550
      • 7.2.6.7 Flavour enhancers      551
      • 7.2.6.8 Disodium Inosinate (IMP)      552
      • 7.2.6.9 Disodium Guanylate (GMP)  553
      • 7.2.6.10            Monatin             554
    • 7.2.7    Bio-based monomers and intermediates    554
      • 7.2.7.1 Succinic acid 554
      • 7.2.7.2 1,4-Butanediol (BDO)              555
      • 7.2.7.3 Isoprene            556
      • 7.2.7.4 Ethylene            556
      • 7.2.7.5 Propylene         557
      • 7.2.7.6 Adipic acid      558
      • 7.2.7.7 Acrylic acid     559
      • 7.2.7.8 Sebacic acid  559
      • 7.2.7.9 Genomatica (Geno) acquired by Again         560
      • 7.2.7.10            Hyosung TNC: Bio-BDO production in Vietnam      560
      • 7.2.7.11            17Cicada: FDCA from mixed waste 561
      • 7.2.7.12            C12: Dodecanedioic acid (DDDA)    561
      • 7.2.7.13            1,5-Pentanediamine (PDA)   561
    • 7.2.8    Bio-based polymers  562
      • 7.2.8.1 Polybutylene succinate (PBS)             562
      • 7.2.8.2 Polyamides (nylons)  563
      • 7.2.8.3 Polyethylene furanoate (PEF)              563
      • 7.2.8.4 Polytrimethylene terephthalate (PTT)            564
      • 7.2.8.5 Polyethylene isosorbide terephthalate (PEIT)           566
    • 7.2.9    Bio-based composites and blends  567
      • 7.2.9.1 Wood-plastic composites (WPCs)  567
      • 7.2.9.2 Biofiller-reinforced plastics  568
      • 7.2.9.3 Biofiber-reinforced plastics  568
      • 7.2.9.4 Polymer blends with bio-based components           570
    • 7.2.10 Beauty and Personal Care Chemicals           571
      • 7.2.10.1            Hyaluronic acid production  571
      • 7.2.10.2            Squalene and Squalane alternatives              572
      • 7.2.10.3            Collagen           573
      • 7.2.10.4            Bio-based UV filters and photoprotective compounds      574
      • 7.2.10.5            Melanin             575
      • 7.2.10.6            Emollients       576
    • 7.2.11 Waste 577
      • 7.2.11.1            Food waste      577
      • 7.2.11.2            Agricultural waste       578
      • 7.2.11.3            Forestry waste               578
      • 7.2.11.4            Aquaculture/fishing waste    579
      • 7.2.11.5            Municipal solid waste              579
      • 7.2.11.6            Industrial waste           580
      • 7.2.11.7            Waste oils        580
      • 7.2.11.8            Recycling and circularity developments (2026)      581
      • 7.2.11.9            Biomason: biocement             581
      • 7.2.12 Microbial and mineral sources           581
        • 7.2.12.1            Microalgae      581
        • 7.2.12.2            Macroalgae     582
        • 7.2.12.3            Cyanobacteria              582
        • 7.2.12.4            Mineral sources            583
    • 7.2.13 Other Bio-manufactured Products  584
      • 7.2.13.1            Cement alternatives from biomanufacturing           584
      • 7.2.13.2            Precision fermentation products      585
  • 7.3        Market analysis            586
    • 7.3.1    Key players and competitive landscape      586
      • 7.3.1.1 Company landscape in specialty chemicals biotechnology          587
      • 7.3.1.2 Bio-manufactured beauty ingredient production capacities          588
    • 7.3.2    Market Growth Drivers and Trends   589
      • 7.3.2.1 Trends and drivers in biotechnology               589
      • 7.3.2.2 Government support of biotechnology         590
      • 7.3.2.3 Carbon taxes  591
    • 7.3.3    Regulations     592
    • 7.3.4    Value chain     593
      • 7.3.4.1 Economic viability factors     593
      • 7.3.4.2 Effect of feedstock prices      594
      • 7.3.4.3 Scale-up effects on cost        595
    • 7.3.5    Future outlook              596
    • 7.3.6    Technology Readiness Level (TRL)   597
    • 7.3.7    Addressable Market Size        598
    • 7.3.8    Risks and Opportunities         599
    • 7.3.9    Major market challenges        599
    • 7.3.10 Technical challenges 600
    • 7.3.11 Global revenues           601
      • 7.3.11.1            By type                601
      • 7.3.11.2            By application market              602
      • 7.3.11.3            By regional market      602
  • 7.4        Company profiles       603

 

8             BIO-AGRITECH             622

  • 8.1        Overview           622
  • 8.2        Technology/materials analysis          623
    • 8.2.1    Biopesticides 623
      • 8.2.1.1 Semiochemical            624
      • 8.2.1.2 Macrobial Biological Control Agents              624
      • 8.2.1.3 Microbial pesticides  627
      • 8.2.1.4 Biochemical pesticides          628
      • 8.2.1.5 Plant-incorporated protectants (PIPs)           628
    • 8.2.2    Biofertilizers   629
    • 8.2.3    Biostimulants 630
      • 8.2.3.1 Microbial biostimulants         630
        • 8.2.3.1.1           Nitrogen Fixation         632
        • 8.2.3.1.2           Formulation Challenges         634
      • 8.2.3.2 Natural Product Biostimulants          634
      • 8.2.3.3 Manipulating the Microbiome             637
      • 8.2.3.4 Synthetic Biology        638
      • 8.2.3.5 Non-microbial biostimulants             639
    • 8.2.4    Agricultural Enzymes                640
      • 8.2.4.1 Types of Agricultural Enzymes            640
  • 8.3        Market analysis            641
    • 8.3.1    Key players and competitive landscape      641
    • 8.3.2    Market Growth Drivers and Trends   642
    • 8.3.3    Regulations     643
    • 8.3.4    Value chain     643
    • 8.3.5    Future outlook              644
    • 8.3.6    Addressable Market Size        645
    • 8.3.7    Risks and Opportunities         645
    • 8.3.8    Global revenues           646
      • 8.3.8.1 By application market              646
      • 8.3.8.2 By regional market      647
  • 8.4        Company profiles       647

 

9             RESEARCH METHODOLOGY              671

 

10          REFERENCES 671

 

List of Tables

  • Table 1. Biomanufacturing revolutions and representative products.      28
  • Table 2. Industrial Biomanufacturing categories.  29
  • Table 3. Overview of Biomanufacturing Processes.             30
  • Table 4. Continuous vs batch biomanufacturing   31
  • Table 5. Key Components of Industrial Biomanufacturing.             31
  • Table 6. Colours of biotechnology.  33
  • Table 7. AI and Robotics Applications in Biomanufacturing           39
  • Table 8. Advanced Technologies in Biomanufacturing Applications.       41
  • Table 9. Types of Cell Culture Systems.       47
  • Table 10. Factors Affecting Cell Culture Performance.      48
  • Table 11. Types of Fermentation Processes.             49
  • Table 12. Factors Affecting Fermentation Performance.   50
  • Table 13. Advances in Fermentation Technology.   50
  • Table 14. Continuous vs Batch Biomanufacturing Comparison. 52
  • Table 15. Types of Purification Methods in Downstream Processing.       53
  • Table 16. Factors Affecting Purification Performance.        53
  • Table 17. Advances in Purification Technology.       54
  • Table 18. Downstream Processing Technology Improvements.    56
  • Table 19. TFF Applications in Downstream Processing.    56
  • Table 20. Common formulation methods used in biomanufacturing.     57
  • Table 21. Factors Affecting Formulation Performance.      57
  • Table 22. Advances in Formulation Technology.     58
  • Table 23. Factors Affecting Scale-up Performance in Biomanufacturing.             59
  • Table 24. Scale-up Strategies in Biomanufacturing.            60
  • Table 25. Factors Affecting Optimization Performance in Biomanufacturing.    61
  • Table 26. Optimization Strategies in Biomanufacturing.   61
  • Table 27. Machine Learning Applications in Biomanufacturing   63
  • Table 28. High-Cell-Density Fermentation Parameters and Targets.         64
  • Table 29. Hybrid Biotechnological-Chemical Process Applications.        66
  • Table 30. Types of Quality Control Tests in Biomanufacturing.     68
  • Table 31. Factors Affecting Quality Control Performance in Biomanufacturing 70
  • Table 32. Types of Characterization Methods in Biomanufacturing.         71
  • Table 33. Factors Affecting Characterization Performance in Biomanufacturing             72
  • Table 34. DNA Synthesis Technologies and Capabilities. 73
  • Table 35. CRISPR-Cas9 Applications in Biomanufacturing.           74
  • Table 36. Protein Engineering Strategies and Applications.             75
  • Table 37. Computer-Aided Design Tools in Biotechnology.              76
  • Table 38. Strain Engineering Strategies and Targets.            77
  • Table 39. Automation Applications in Biotechnology.         78
  • Table 40. AI/ML Applications in Biomanufacturing Systems.         79
  • Table 41. C1 Feedstock Utilization Pathways and Characteristics.            80
  • Table 42. C2 Feedstock Processing and Applications.       80
  • Table 43. Lignocellulosic Biomass Processing Technologies.        81
  • Table 44. Blue Biotechnology Feedstock Characteristics and Applications.       82
  • Table 45. Carbon Capture and Utilization Pathways in Biotechnology.   84
  • Table 46. Key fermentation parameters in batch vs continuous biomanufacturing processes.              90
  • Table 47. Key fermentation parameter comparison             93
  • Table 48. Major microbial cell factories used in industrial biomanufacturing.   95
  • Table 49. Organism Categories and Production Capabilities.       96
  • Table 50. E. coli Characteristics for Biomanufacturing Applications.      97
  • Table 51. C. glutamicum Production Capabilities and Characteristics.  98
  • Table 52. B. subtilis Production Systems and Applications.           99
  • Table 53. S. cerevisiae Capabilities and Industrial Applications. 100
  • Table 54. Y. lipolytica Production Capabilities and Process Parameters.               101
  • Table 55. Non-Model Organisms and Specialized Applications. 102
  • Table 56. Perfusion Bioreactor Technologies and Performance.  104
  • Table 57. Enzyme Immobilization Methods and Characteristics. 106
  • Table 58. Immobilized Catalyst Systems and Applications.            107
  • Table 59. Comparison of Modes of Operation.        108
  • Table 60. Host organisms commonly used in biomanufacturing.               108
  • Table 61. Types of biopharmaceuticals.      110
  • Table 62. Types of Monoclonal Antibodies. 111
  • Table 63. Types of Recombinant Proteins.  111
  • Table 64. Types of biopharma vaccines.      112
  • Table 65. Types of Cell and Gene Therapies              112
  • Table 66. Types of Blood Factors.     113
  • Table 67. Types of Tissue Engineering Products.     113
  • Table 68. Types of Nucleic Acid Therapeutics.         114
  • Table 69. Types of Peptide Therapeutics.    115
  • Table 70. Types of Biosimilars and Biobetters.         115
  • Table 71. Types of Nanobodies and Antibody Fragments. 116
  • Table 72. Types of Synthetic Biology Applications in Biopharmaceuticals.          116
  • Table 73. Engineered proteins in industrial applications. 120
  • Table 74. Cell-free versus cell-based systems         123
  • Table 75. White biotechnology fermentation processes.  128
  • Table 76. Key players in biopharmaceuticals.          139
  • Table 77. Market Growth Drivers and Trends in Biopharmaceuticals.      140
  • Table 78. Biopharmaceuticals Regulations.              141
  • Table 79. Value chain: Biopharmaceuticals.            142
  • Table 80. Technology Readiness Level (TRL): Biopharmaceuticals.          143
  • Table 81. Addressable market size for biopharmaceuticals.          145
  • Table 82. Risks and Opportunities in biopharmaceuticals.             145
  • Table 83. Global revenues for biopharmaceuticals, by applications market (2020-2037), billions USD.                147
  • Table 84. Global revenues for biopharmaceuticals, by regional market (2020-2037), billions USD.    148
  • Table 85. Biopharmaceuticals company profiles. 148
  • Table 86. Types of industrial enzymes.          170
  • Table 87. Types of Detergent Enzymes.        171
  • Table 88. Types of Food Processing Enzymes           172
  • Table 89. Types of Textile Processing Enzymes.      172
  • Table 90. Types of Paper and Pulp Processing Enzymes.  173
  • Table 91. Types of Leather Processing Enzymes.   173
  • Table 92. Types of Biofuel Production Enzymes.     174
  • Table 93. Lignocellulosic Enzyme Systems and Performance.      175
  • Table 94. Cellulase Component Functions and Characteristics. 176
  • Table 95. Hemicellulase Systems and Substrate Specificity.         177
  • Table 96. Thermostable Enzyme Sources and Characteristics.    178
  • Table 97. Thermostable Enzyme Economic Analysis Framework.               179
  • Table 98. Types of Animal Feed Enzymes.   179
  • Table 99. Types of Pharmaceutical and Diagnostic Enzymes.       180
  • Table 100. Types of Waste Management and Bioremediation Enzymes. 180
  • Table 101. Enzymes for Plastics Recycling Applications.  182
  • Table 102. Challenges in Enzymatic Depolymerization.     183
  • Table 103. Types of Agriculture and Crop Improvement Enzymes.             184
  • Table 104. Comparison of enzyme types.    184
  • Table 105. Enzymes for Decarbonization and CO₂ Utilization.      186
  • Table 106. Carbonic Anhydrase Applications in CO₂ Capture.      188
  • Table 107. Formate Dehydrogenase Systems for CO₂ Conversion.            189
  • Table 108. Enzymatic CO₂ Capture and Conversion Technologies.            190
  • Table 109. Key players in industrial enzymes.          190
  • Table 110. Market Growth Drivers and Trends in industrial enzymes.       191
  • Table 111. Technology Challenges and Opportunities for Industrial Enzymes.  192
  • Table 112. Industrial enzymes Regulations.              194
  • Table 113. Value chain: Industrial enzymes.             195
  • Table 114. Technology Readiness Level (TRL): Biocatalysts.          197
  • Table 115. Addressable market size for industrial enzymes.          198
  • Table 116. Risks and Opportunities in industrial enzymes.             198
  • Table 117. Global revenues for industrial enzymes, by applications market (2020-2037), billions USD.                199
  • Table 118. Global revenues for industrial enzymes, by regional market (2020-2037), billions USD.     199
  • Table 119. Industrial Enzymes Company Profiles. 200
  • Table 120. Types of biofuel, by generation. 213
  • Table 121. Comparison of biofuels. 216
  • Table 122. Classification of biomass feedstock.    217
  • Table 123. Biorefinery feedstocks.   218
  • Table 124. Feedstock conversion pathways.             218
  • Table 125. First-Generation Feedstocks.     218
  • Table 126. Lignocellulosic ethanol plants and capacities.              221
  • Table 127. Comparison of pulping and biorefinery lignins.              222
  • Table 128. Commercial and pre-commercial biorefinery lignin production facilities and processes  222
  • Table 129. Operating and planned lignocellulosic biorefineries and industrial flue gas-to-ethanol.   224
  • Table 130. Properties of microalgae and macroalgae.       227
  • Table 131. Yield of algae and other biodiesel crops.            228
  • Table 132. Advantages and disadvantages of biofuels, by generation.    229
  • Table 133. Biodiesel by generation. 231
  • Table 134. Biodiesel production techniques.            232
  • Table 135. Summary of pyrolysis technique under different operating conditions.         233
  • Table 136. Biomass materials and their bio-oil yield.          235
  • Table 137. Biofuel production cost from the biomass pyrolysis process.              236
  • Table 138. Properties of vegetable oils in comparison to diesel.  237
  • Table 139. Main producers of HVO and capacities.              238
  • Table 140. Commercial development of BtL processes     240
  • Table 141. Pilot or demo projects for biomass to liquid (BtL) processes.               241
  • Table 142.Biodiesel (B20) average prices, current and historical, USD/litre.        243
  • Table 143. Global biodiesel consumption, 2010–2037 (M litres/year)      244
  • Table 144. Biogas and biomethane feedstock          247
  • Table 145. Existing and planned bio-LNG production plants.        253
  • Table 146. Methods for capturing carbon dioxide from biogas.    254
  • Table 147. Total syngas market by product 255
  • Table 148. Biosyngas price ranges by application: 256
  • Table 149. Comparison of different Bio-H2 production pathways.             262
  • Table 150. Markets and applications for biohydrogen.       264
  • Table 151. Comparison of biogas, biomethane and natural gas. 268
  • Table 152. Summary of applications of biochar in energy.               272
  • Table 153. Typical composition and physicochemical properties reported for bio-oils and heavy petroleum-derived oils.          273
  • Table 154. Properties and characteristics of pyrolysis liquids derived from biomass versus a fuel oil.                273
  • Table 155. Main techniques used to upgrade bio-oil into higher-quality fuels.   275
  • Table 156. Markets and applications for bio-oil.     275
  • Table 157. Bio-oil producers.              276
  • Table 158. Global renewable diesel consumption, 2010-2037 (M litres/year).   279
  • Table 159. Renewable diesel price ranges  280
  • Table 160. Advantages and disadvantages of Bio-aviation fuel.   281
  • Table 161. Production pathways for Bio-aviation fuel.        284
  • Table 162. Current and announced Bio-aviation fuel facilities and capacities. 285
  • Table 163. Global bio-jet fuel consumption, 2019–2037 (million litres/year)       286
  • Table 164. production cost estimates and projections      290
  • Table 165. Algae-derived biofuel producers.             291
  • Table 166. Key players in biofuels.   292
  • Table 167. Market Growth Drivers and Trends in biofuels.               295
  • Table 168. Biofuels Regulations.       295
  • Table 169. Value chain: Biofuels.      297
  • Table 170. Technology Readiness Level (TRL): Biofuels.   299
  • Table 171. Addressable market size, billions USD 300
  • Table 172. Risks and Opportunities in biofuels       301
  • Table 173. Global revenues for biofuels, by type (2020-2037), billions USD.       301
  • Table 174. Global Revenues for Biofuels, by Applications Market (2020-2037), billions USD. 302
  • Table 175. Global revenues for biofuels, by regional market (2020-2037), billions USD.             302
  • Table 176. Biofuels Company Profiles.         302
  • Table 177. Types of bioplastics:        352
  • Table 178. Polylactic acid (PLA) market analysis-manufacture, advantages, disadvantages and applications.  353
  • Table 179. Types of PHAs and properties.   357
  • Table 180. Commercially available PHAs.  358
  • Table 181. Markets and applications for PHAs.       358
  • Table 182. Bio-based Polyethylene (Bio-PE) market analysis- manufacture, advantages, disadvantages and       361
  • Table 183. Bio-based Polyethylene terephthalate (Bio-PET) market analysis- manufacture, advantages,                361
  • Table 184. Bio-based Polyethylene terephthalate (PET) producers and production capacities,             362
  • Table 185. Key players in Bioplastics.            365
  • Table 186. Market Growth Drivers and Trends in Bioplastics.        366
  • Table 187. Bioplastics Regulations. 367
  • Table 188. Value chain: Bioplastics.               367
  • Table 189. Technology Readiness Level (TRL): Bioplastics.            369
  • Table 190. Addressable market size for Bioplastics.            371
  • Table 191. Risks and Opportunities in Bioplastics.              371
  • Table 192. Global revenues for bioplastics, by type (2020-2037), billions USD. 372
  • Table 193. Global revenues for bioplastics, by applications market (2020-2037), billions USD.            372
  • Table 194. Global revenues for bioplastics, by regional market (2020-2037), billions USD.      373
  • Table 195. Bioplastics Company Profiles.  373
  • Table 196. Types of biochemicals.   517
  • Table 197. Plant-based feedstocks and biochemicals produced.               519
  • Table 198. Waste-based feedstocks and biochemicals produced.            520
  • Table 199. Microbial and mineral-based feedstocks and biochemicals produced.         521
  • Table 200. Biobased feedstock sources for Succinic acid.              523
  • Table 201. Applications of succinic acid.    523
  • Table 202. Biobased feedstock sources for itaconic acid.               524
  • Table 203. Applications of bio-based itaconic acid.            524
  • Table 204. Feedstock Sources for Citric Acid Production.               525
  • Table 205. Applications of Citric Acid.           525
  • Table 206. Feedstock Sources for Acetic Acid Production.             525
  • Table 207. Applications of Acetic Acid.         525
  • Table 208. Feedstock Sources for Acetic Acid Production.             526
  • Table 209. Applications of Acetic Acid.         526
  • Table 210. Common lysine sources that can be used as feedstocks for producing biochemicals.      527
  • Table 211. Applications of lysine as a feedstock for biochemicals.           527
  • Table 212. Feedstock Sources for Threonine Production. 528
  • Table 213. Applications of Threonine.           528
  • Table 214. Feedstock Sources for Methionine Production.             529
  • Table 215. Applications of Methionine.        529
  • Table 216. Vitamins Produced Using Biotechnology.          529
  • Table 217. Biobased feedstock sources for ethanol.           534
  • Table 218. Applications of bio-based ethanol.        534
  • Table 219. Feedstock Sources for Butanol Production.     535
  • Table 220. Applications of Butanol. 535
  • Table 221. Biobased feedstock sources for isobutanol.    535
  • Table 222. Applications of bio-based isobutanol. 536
  • Table 223. Applications of bio-based 1,3-Propanediol (1,3-PDO).             536
  • Table 224. Types of Biosurfactants. 537
  • Table 225. Feedstock Sources for Biosurfactant Production          537
  • Table 226. Applications of Biosurfactants  537
  • Table 227. Rhamnolipid Production and Application Characteristics.     538
  • Table 228. Sophorolipid Types and Application Properties.             539
  • Table 229. Mannosylerythritol Lipid Variants and Properties.        540
  • Table 230. Cellobiose Lipid Development and Applications.         541
  • Table 231. Designer Biosurfactant Engineering Strategies               542
  • Table 232. Feedstock Sources for APG Production               543
  • Table 233. Applications of Alkyl Polyglucosides (APGs)     543
  • Table 234. Feedstock Sources for Ethyl Lactate Production.         544
  • Table 235. Applications of Ethyl Lactate.     544
  • Table 236. Feedstock Sources for Dimethyl Carbonate Production           544
  • Table 237. Applications of Dimethyl Carbonate      544
  • Table 238. Markets and applications for bio-based glycerol.          545
  • Table 239. Bio-manufactured Fragrances and Aromatics.               549
  • Table 240. Biotech-derived Fragrance Precursors.                550
  • Table 241. Bio-manufactured Enhancers.  552
  • Table 242. Feedstock Sources for Succinic Acid Production          555
  • Table 243. Applications of Succinic Acid.   555
  • Table 244. Applications of bio-based 1,4-Butanediol (BDO).        555
  • Table 245. Feedstock Sources for Isoprene Production.   556
  • Table 246. Applications of Isoprene.              556
  • Table 247. Applications of bio-based ethylene.       557
  • Table 248. Applications of bio-based propylene.   557
  • Table 249. Applications of bio-based adipic acid. 558
  • Table 250. Applications of bio-based acrylic acid.                559
  • Table 251. Bio-PBS market analysis-manufacture, advantages, disadvantages and applications.      562
  • Table 252. Leading PBS producers and production capacities.   562
  • Table 253. Polyethylene furanoate (PEF) market analysis-manufacture, advantages, disadvantages and applications.  563
  • Table 254. FDCA and PEF producers.            564
  • Table 255. Polytrimethylene terephthalate (PTT) market analysis-manufacture, advantages, disadvantages and    565
  • Table 256. Production capacities of Polytrimethylene terephthalate (PTT), by leading producers.       565
  • Table 257. Types of Wood-Plastic Composites (WPCs).    567
  • Table 258. Types of Biofiber-Reinforced Plastics.  569
  • Table 259. Types of Polymer Blends with Bio-based Components.           570
  • Table 260. Hyaluronic Acid Production Parameters and Applications     572
  • Table 261. Squalene/Squalane Production Methods and Characteristics.           573
  • Table 262. Collagen Production Systems and Applications.          574
  • Table 263. Bio-based UV Filter Compounds and Characteristics.              575
  • Table 264. Melanin Production and Application Parameters.        576
  • Table 265. Bio-manufactured Emollient Categories and Properties.         577
  • Table 266. Mineral source products and applications.       583
  • Table 267. Cement Alternatives from Biomanufacturing. 584
  • Table 268. Precision Fermentation Products.           585
  • Table 269. Key players in Biochemicals.      586
  • Table 270. Bio-manufactured Beauty Ingredient Production Capacities                589
  • Table 271. Market Growth Drivers and Trends in Biochemicals.  589
  • Table 272. Trends and Drivers in Biotechnology.    590
  • Table 273. Government Support of Biotechnology.              591
  • Table 274. Biochemicals Regulations.          592
  • Table 275. Value chain: Biochemicals.         593
  • Table 276. Economic Viability Assessment Framework.   594
  • Table 277. Feedstock Price Impact Analysis for Biotechnology Production.        595
  • Table 278. Scale-up Cost Impact Analysis.               596
  • Table 279. Addressable market size for Biochemicals.      598
  • Table 280. Risks and Opportunities in Biochemicals.         599
  • Table 281. Market Challenge Assessment and Mitigation Strategies.       600
  • Table 282. Technical Challenge Assessment and Solutions.         601
  • Table 283. Global revenues for biochemicals, by type (2020-2037), billions USD.          601
  • Table 284. Global revenues for biochemicals, by applications market (2020-2037), billions USD.       602
  • Table 285. Global revenues for biochemicals, by regional market (2020-2037), billions USD. 602
  • Table 286. Biochemicals Company Profiles.             603
  • Table 287. Bio-agritech categories. 622
  • Table 288. Biopesticides: Pros and Cons.   623
  • Table 289. Semiochemicals: Advantages and Disadvantages.    624
  • Table 290. Biological Pest Control: Advantages and Disadvantages.       625
  • Table 291. Global regulations on biopesticides.     625
  • Table 292. Main types of microbial pesticides.        627
  • Table 293. Main types of biochemical pesticides. 628
  • Table 294. Main types of biofertilizers.          629
  • Table 295. Types of Microbial Biostimulants.           635
  • Table 296. Main types of non-microbial biostimulants.     639
  • Table 297. Types of Agricultural Enzymes   640
  • Table 298. Key players in Bio Agritech.          642
  • Table 299. Market Growth Drivers and Trends in Bio Agritech        642
  • Table 300. Bio Agritech Regulations.              643
  • Table 301. Value chain: Bio Agritech.             643
  • Table 302. Addressable market size for Bio Agritech.          645
  • Table 303. Risks and Opportunities in Bio Agritech.             645
  • Table 304. Global revenues for Bio Agritech products, by applications market (2020-2037), billions USD.                646
  • Table 305. Global revenues for Bio Agritech products, by regional market (2020-2037), billions USD.                647
  • Table 306. Bio agritech Company Profiles. 647
  •  

List of Figures

  • Figure 1. CRISPR/Cas9 & Targeted Genome Editing.           119
  • Figure 2. Genetic Circuit-Assisted Smart Microbial Engineering. 122
  • Figure 3. Cell-free and cell-based protein synthesis systems.      124
  • Figure 4. Microbial Chassis Development for Natural Product Biosynthesis.     125
  • Figure 5. The design-make-test-learn loop of generative biology.                129
  • Figure 6. Flow chart for biodiesel production.          236
  • Figure 7. Biogas and biomethane pathways.             246
  • Figure 8. Overview of biogas utilization.       248
  • Figure 9. Biogas and biomethane pathways.             250
  • Figure 10. Schematic overview of anaerobic digestion process for biomethane production.   251
  • Figure 11. Schematic overview of biomass gasification for biomethane production.    252
  • Figure 12. Properties of petrol and biobutanol.       257
  • Figure 13. Biobutanol production route.      257
  • Figure 14. Renewable Methanol Production Processes from Different Feedstocks.       267
  • Figure 15. Production of biomethane through anaerobic digestion and upgrading.        268
  • Figure 16. Production of biomethane through biomass gasification and methanation.               269
  • Figure 17. Production of biomethane through the Power to methane process.  269
  • Figure 18. Bio-oil upgrading/fractionation techniques.      275
  • Figure 19. SWOT analysis for Bio-aviation fuel.       283
  • Figure 20. Pathways for algal biomass conversion to biofuels.     287
  • Figure 21. SWOT analysis for algae-derived biofuels.         288
  • Figure 22. Algal biomass conversion process for biofuel production.      289
  • Figure 23. PHA family.              357
  • Figure 24. Schematic of biorefinery processes.      522
  • Figure 25. Production capacities of Polyethylene furanoate (PEF) to 2025.          564
  • Figure 26. Technology Readiness Level (TRL): Biochemicals.        598

 

 

The Global Industrial Biomanufacturing Market 2027-2037
The Global Industrial Biomanufacturing Market 2027-2037
PDF + Excel.

The Global Industrial Biomanufacturing Market 2027-2037
The Global Industrial Biomanufacturing Market 2027-2037
PDF + Excel + Print Edition (including tracked delivery).

 

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